Acceclomax-MR Tablet
Active Composition
About Acceclomax-MR Tablet
Acceclomax-MR Tablet is a combination medication used to relieve pain and inflammation in conditions like arthritis, muscle pain, and other musculoskeletal disorders. It contains Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol, an analgesic. This medicine is typically prescribed for adults and should be used under medical supervision. It helps in reducing pain and swelling, improving the quality of life for those with chronic pain conditions.
Clinical Uses
- Osteoarthritis — A degenerative joint disease causing pain and stiffness.
- Rheumatoid Arthritis — An autoimmune disorder causing joint inflammation.
- Ankylosing Spondylitis — A type of arthritis affecting the spine.
- Muscle Pain — Pain resulting from muscle strain or injury.
Uses & Indications
Primary Uses
Pain relief in arthritis
Reduction of inflammation in musculoskeletal conditions
Secondary Uses
Relief from dental pain
Management of post-operative pain
Off-label Uses
Relief from headache
How It Works (Mechanism of Action)
Acceclomax-MR Tablet works by combining the effects of Aceclofenac and Paracetamol. Aceclofenac reduces pain and inflammation by inhibiting the production of chemical messengers called prostaglandins. Paracetamol helps in reducing fever and enhances pain relief.
Scientifically, Aceclofenac is a non-selective COX inhibitor, which blocks the cyclooxygenase (COX) enzymes involved in the synthesis of prostaglandins. Paracetamol works centrally in the brain to block the production of prostaglandins and also acts on the hypothalamus to regulate body temperature.
Key Benefits
- Pain Relief — Helps reduce pain in various conditions.
- Anti-inflammatory — Reduces swelling and inflammation.
- Improved Mobility — Eases movement by reducing joint stiffness.
How Long Does It Take to Work?
Initial improvement in pain and inflammation can be noticed within 1-2 hours after taking the tablet. Full therapeutic effects may take a few days of consistent use. If there is no improvement after a week, consult your doctor.
How to Use
Take the tablet with a full glass of water.
Swallow the tablet whole; do not crush or chew.
Take it with or after food to minimize stomach upset.
Follow the dosage prescribed by your doctor.
Do not exceed the recommended dose.
Dosage Guidelines
Adult Dose
Typically, one tablet twice a day.
Pediatric Dose
Not recommended for children.
Elderly
Use with caution; dosage adjustment may be necessary.
Administration Instructions
Take with food to reduce gastrointestinal discomfort.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Overdose Warning
In case of overdose, symptoms may include nausea, vomiting, stomach pain, dizziness, or drowsiness. Seek immediate medical attention or contact a poison control center.
Side Effects
Common Side Effects
Nausea
Indigestion
Dizziness
Less Common Side Effects
Diarrhea
Constipation
Serious Side Effects
Allergic reactions like rash, itching, or swelling
Severe stomach pain
Yellowing of the skin or eyes
When to Seek Immediate Medical Attention
Signs of an allergic reaction
Severe abdominal pain
Difficulty breathing
Contraindications — Who Should Not Use This Medicine
- Allergy to NSAIDs — Patients with known hypersensitivity should avoid use.
- Severe Liver Impairment — Can worsen liver function.
- Severe Kidney Impairment — May lead to further kidney damage.
- Active Peptic Ulcer — Increases risk of bleeding.
Warnings & Precautions
Drug Interactions
Drug-Drug Interactions
Warfarin
Other NSAIDs
Corticosteroids
Diuretics
Food Interactions
Take with food to reduce stomach irritation.
Alcohol Interactions
Avoid alcohol to prevent increased risk of liver damage.
Disease Interactions
Peptic Ulcer Disease
Liver Disease
Kidney Disease
Storage Instructions
Store at room temperature (15-25°C).
Keep away from moisture and light.
Keep out of reach of children.
Check the expiry date before use.
Expert Advice
Complete the full course as prescribed.
Take with food to reduce stomach upset.
Do not share your medication with others.
Inform your doctor about all other medications you are taking.
Do not consume alcohol while on this medication.
Report any unusual symptoms to your doctor immediately.
Do not take more than the recommended dose.
Consult your doctor if pain persists or worsens.
Keep hydrated while taking this medication.
Substitute Medicines
Same composition, different brands. Always consult your doctor before switching.
Sources
The information on this page about Acceclomax-MR Tablet has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.
- Manufacturer – Acceclomax-MR Tablet Prescribing Information and Product Monograph
- NHS – Aceclofenac: medicine to treat pain and inflammation
- Mayo Clinic – Acetaminophen (Oral Route)
- MedlinePlus – Acetaminophen
- Drugs.com – Aceclofenac