Ace Plus Tablet

Ace Plus Tablet is a combination medication that contains Aceclofenac and Paracetamol. It is used to relieve pain and inflammation in conditions like arthritis, back pain, and dental pain. This medicine is suitable for adults and should be taken as prescribed by a healthcare professional. It works by reducing the production of certain chemicals in the body that cause pain and inflammation. Patients with liver or kidney issues should consult their doctor before use.

• Arthritis — Helps reduce pain and inflammation associated with arthritis.
• Back Pain — Provides relief from acute back pain.
• Dental Pain — Eases pain following dental procedures or toothaches.

Primary Uses

Relief of pain and inflammation in arthritis.

Management of acute back pain.

Reduction of dental pain.

Secondary Uses

Relief from muscle pain.

Management of mild to moderate pain due to injury.

Off-label Uses

Not typically used for off-label purposes.

Ace Plus Tablet works by combining the effects of Aceclofenac and Paracetamol. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain by blocking the action of cyclooxygenase, an enzyme involved in the production of prostaglandins. Paracetamol works by inhibiting the synthesis of prostaglandins in the brain, which helps in reducing pain and fever.

Scientifically, Aceclofenac inhibits the COX-1 and COX-2 enzymes, leading to decreased formation of prostaglandins, which are mediators of inflammation and pain. Paracetamol's antipyretic and analgesic effects are primarily due to its action on the central nervous system, where it inhibits the synthesis of prostaglandins.

• Pain Relief — Provides effective relief from various types of pain.
• Anti-inflammatory — Reduces inflammation in conditions like arthritis.
• Combination Therapy — Combines two active ingredients for enhanced effect.

Initial improvement in pain relief can be noticed within 30 minutes to 1 hour after taking the tablet. Full therapeutic effect may take a few days of regular use. If there is no improvement in symptoms after 3-5 days, consult your doctor.

Take the tablet orally with a glass of water.

Swallow the tablet whole; do not crush or chew.

Take it with or after food to avoid stomach upset.

Follow the dosage as prescribed by your doctor.

Do not exceed the recommended dose.

Adult Dose

Typically, one tablet twice daily.

Pediatric Dose

Not recommended for children under 12 years.

Elderly

Use with caution; dose adjustment may be necessary.

Administration Instructions

Take with food to minimize gastrointestinal discomfort.

Common Side Effects

Stomach pain

Nausea

Diarrhea

Less Common Side Effects

Dizziness

Rash

Serious Side Effects

Allergic reactions like swelling of face, lips, or throat

Severe skin reactions

When to Seek Immediate Medical Attention

Difficulty breathing

Severe abdominal pain

• Allergy to NSAIDs — Patients with known hypersensitivity to Aceclofenac or Paracetamol should not use this medicine.
• Severe Liver Disease — Not recommended for patients with severe liver impairment.
• Active Peptic Ulcer — Avoid in patients with active ulcer disease.

Drug-Drug Interactions

Warfarin

Other NSAIDs

Antihypertensive drugs

Food Interactions

Take with food to reduce stomach upset.

Alcohol Interactions

Avoid alcohol to prevent increased risk of liver damage.

Disease Interactions

Liver disease

Kidney disease

Store at room temperature (15-30°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check expiry date before use.