Acecloflam 100 mg/325 mg/250 mg Tablet

Acecloflam 100 mg/325 mg/250 mg Tablet is a combination medication used to relieve pain and inflammation. It contains Aceclofenac, a nonsteroidal anti-inflammatory drug (NSAID), and Paracetamol, a common pain reliever. This medicine is typically prescribed for conditions such as arthritis, muscle pain, and other inflammatory conditions. Patients experiencing mild to moderate pain can benefit from this medication. It is important to follow the doctor's instructions and not exceed the recommended dosage to avoid potential side effects.

• Osteoarthritis — Reduces pain and inflammation in joints.
• Rheumatoid Arthritis — Alleviates symptoms of joint inflammation and pain.
• Ankylosing Spondylitis — Eases pain and stiffness in the spine.
• Musculoskeletal Pain — Provides relief from muscle pain and discomfort.

Primary Uses

Relief from joint pain and inflammation in arthritis.

Reduction of muscle pain and discomfort.

Secondary Uses

Management of pain due to minor injuries.

Relief from dental pain.

Off-label Uses

Acecloflam works by combining the effects of Aceclofenac and Paracetamol. Aceclofenac reduces inflammation and pain by inhibiting the enzymes that produce prostaglandins, which are responsible for inflammation. Paracetamol works by blocking chemical messengers in the brain that signal pain.

Scientifically, Aceclofenac is a selective inhibitor of cyclooxygenase (COX) enzymes, particularly COX-2, which decreases the formation of pro-inflammatory chemicals. Paracetamol acts centrally in the brain to inhibit the synthesis of prostaglandins, providing analgesic and antipyretic effects.

• Pain Relief — Effectively reduces mild to moderate pain.
• Anti-inflammatory — Decreases inflammation in joints and muscles.
• Improved Mobility — Helps improve movement in affected areas.

Initial improvement in pain relief can be noticed within 30 minutes to 1 hour after taking the tablet. Full therapeutic effects may take a few days of regular use. If there is no improvement after a few days, or if symptoms worsen, consult your doctor.

Take the tablet as prescribed by your doctor, usually once or twice daily.

Swallow the tablet whole with a glass of water.

Take it with or after food to reduce stomach upset.

Do not crush or chew the tablet.

Follow the prescribed dosage and do not exceed it.

Adult Dose

Typically, one tablet taken once or twice daily, as directed by a physician.

Pediatric Dose

Not recommended for children without medical advice.

Elderly

May require dose adjustment; consult with a healthcare provider.

Administration Instructions

Take with food to minimize gastrointestinal discomfort.

Common Side Effects

Nausea

Indigestion

Diarrhea

Less Common Side Effects

Dizziness

Headache

Serious Side Effects

Allergic reactions such as rash, itching, or swelling

Severe abdominal pain

Yellowing of the skin or eyes

When to Seek Immediate Medical Attention

Signs of an allergic reaction

Severe stomach pain

Difficulty breathing

• Allergy to NSAIDs — Patients with known allergies to NSAIDs should avoid this medication.
• Severe Liver or Kidney Disease — Not recommended due to potential for increased side effects.
• Active Peptic Ulcer — May exacerbate ulcer symptoms.

Drug-Drug Interactions

Warfarin

Aspirin

Other NSAIDs

Food Interactions

Take with food to reduce stomach upset.

Alcohol Interactions

Avoid alcohol to prevent increased risk of liver damage.

Disease Interactions

Peptic Ulcer Disease

Liver Disease

Kidney Disease

Store at room temperature (15-30°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check expiry date before use.