Aceflam P 100mg/325mg Tablet
Active Composition
About Aceflam P 100mg/325mg Tablet
Aceflam P 100mg/325mg Tablet is a combination medication containing Aceclofenac and Paracetamol. It is primarily used to relieve pain and inflammation in conditions such as arthritis, muscle pain, and dental pain. This medicine is suitable for adults and should be taken as prescribed by a healthcare professional. It works by reducing the substances in the body that cause pain and inflammation. Patients with a history of allergies to NSAIDs or paracetamol should avoid this medication.
Clinical Uses
- Arthritis — Helps reduce pain and inflammation in joints.
- Muscle Pain — Provides relief from muscle aches and discomfort.
- Dental Pain — Alleviates pain following dental procedures.
Uses & Indications
Primary Uses
Relief of pain and inflammation in arthritis.
Treatment of muscle pain.
Management of dental pain.
Secondary Uses
Relief from mild to moderate pain from other causes.
Off-label Uses
Not typically used for off-label purposes.
How It Works (Mechanism of Action)
Aceflam P works by combining the effects of Aceclofenac and Paracetamol. Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain by blocking the production of certain chemical messengers in the body. Paracetamol, on the other hand, works centrally in the brain to relieve pain and reduce fever.
Scientifically, Aceclofenac inhibits the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins, substances that mediate inflammation and pain. Paracetamol is believed to inhibit the COX enzyme in the brain, leading to its analgesic and antipyretic effects.
Key Benefits
- Pain Relief — Effectively reduces pain in various conditions.
- Anti-inflammatory — Decreases inflammation, improving mobility and comfort.
- Combination Therapy — Provides dual action through two active ingredients.
How Long Does It Take to Work?
Initial improvement in pain relief can often be felt within 30 minutes to 1 hour after taking the tablet. For full therapeutic effect, it may take a few days of regular use. If there is no improvement in symptoms after a few days, or if symptoms worsen, consult a doctor.
How to Use
Take the tablet orally with a full glass of water.
It can be taken with or without food, but taking it with food may reduce stomach upset.
Follow the dosage instructions provided by your healthcare provider.
Do not crush or chew the tablet; swallow it whole.
Take it at the same time each day to maintain consistent levels in your body.
Dosage Guidelines
Adult Dose
Typically, one tablet taken 1-2 times a day as needed for pain relief.
Pediatric Dose
Not recommended for children without medical advice.
Elderly
Use with caution and under medical supervision due to potential increased risk of side effects.
Administration Instructions
Follow the prescribed dosage and schedule strictly.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up.
Overdose Warning
In case of overdose, symptoms may include nausea, vomiting, stomach pain, dizziness, and confusion. Seek immediate medical attention or contact emergency services or poison control for guidance.
Side Effects
Common Side Effects
Nausea
Dizziness
Indigestion
Less Common Side Effects
Rash
Diarrhea
Serious Side Effects
Allergic reactions such as swelling of the face or throat
Severe abdominal pain
Yellowing of the skin or eyes (jaundice)
When to Seek Immediate Medical Attention
If you experience symptoms of an allergic reaction or severe side effects, seek medical help immediately.
Contraindications — Who Should Not Use This Medicine
- Allergy to NSAIDs or Paracetamol — Can cause severe allergic reactions.
- Severe liver or kidney impairment — May worsen these conditions.
- Active peptic ulcer — Can increase the risk of bleeding.
Warnings & Precautions
Drug Interactions
Drug-Drug Interactions
Anticoagulants (e.g., warfarin)Other NSAIDs
Corticosteroids
Food Interactions
No significant food interactions known.
Alcohol Interactions
Increased risk of liver damage and stomach bleeding.
Disease Interactions
Peptic ulcer disease
Liver disease
Kidney disease
Storage Instructions
Store at room temperature (20-25°C).
Keep away from moisture and light.
Keep out of reach of children.
Check the expiry date before use.
Expert Advice
Do not exceed the recommended dose.
Take with food to reduce stomach upset.
Avoid alcohol while taking this medication.
Inform your doctor about any other medications you are taking.
Do not use if you have a known allergy to NSAIDs or paracetamol.
Consult your doctor if symptoms persist or worsen.
Keep the medication in its original packaging to protect from light.
Do not share your medication with others.
Complete the full course as prescribed by your doctor.
Substitute Medicines
Same composition, different brands. Always consult your doctor before switching.
Sources
The information on this page about Aceflam P 100mg/325mg Tablet has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.
- Manufacturer – Aceflam P 100mg/325mg Tablet Prescribing Information and Product Monograph
- NHS – Aceclofenac: medicine to treat pain and inflammation
- Mayo Clinic – Nonsteroidal anti-inflammatory drugs (NSAIDs)
- MedlinePlus – Paracetamol (Acetaminophen)
- Drugs.com – Aceclofenac and Paracetamol