Acenate-SP Tablet
Active Composition
About Acenate-SP Tablet
Acenate-SP Tablet is a combination medicine containing Aceclofenac and Paracetamol. It is primarily used to relieve pain and inflammation in conditions such as arthritis, muscle pain, and dental pain. The tablet helps reduce pain and swelling, making it easier for patients to carry out daily activities. It is suitable for adults and should be taken under the guidance of a healthcare professional. This medicine is not recommended for children unless prescribed by a doctor.
Clinical Uses
- Arthritis — Helps reduce pain and inflammation in joint conditions.
- Muscle Pain — Alleviates discomfort in muscles.
- Dental Pain — Provides relief from toothache and related pain.
Uses & Indications
Primary Uses
Relief of pain and inflammation in arthritis.
Management of muscle pain.
Alleviation of dental pain.
Secondary Uses
Relief from mild to moderate pain from other causes.
Off-label Uses
How It Works (Mechanism of Action)
Acenate-SP Tablet works by combining the effects of Aceclofenac and Paracetamol. Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain by blocking the production of certain chemical messengers in the body. Paracetamol is an analgesic that helps reduce fever and enhance pain relief.
Scientifically, Aceclofenac inhibits cyclooxygenase (COX) enzymes, which are involved in the synthesis of prostaglandins, leading to reduced inflammation and pain. Paracetamol works centrally in the brain to block pain signals and reduce fever by acting on the hypothalamus.
Key Benefits
- Pain Relief — Effectively reduces pain from various conditions.
- Reduces Inflammation — Helps decrease swelling and inflammation.
- Improves Mobility — Eases movement by alleviating pain and stiffness.
How Long Does It Take to Work?
Initial improvement in pain and inflammation can be observed within 30 minutes to 1 hour after taking the tablet. Full therapeutic effects may take a few days of consistent use. If there is no improvement in symptoms after a few days, consult your doctor for further evaluation.
How to Use
Take the tablet as prescribed by your doctor.
Swallow the tablet whole with a glass of water.
It can be taken with or without food.
Follow the dosage schedule strictly to avoid missing doses.
Do not crush or chew the tablet.
Dosage Guidelines
Adult Dose
Typically, one tablet twice daily or as directed by a physician.
Pediatric Dose
Not recommended for children unless prescribed by a doctor.
Elderly
Use with caution; dosage may need adjustment based on renal and liver function.
Administration Instructions
Take with a full glass of water.
Do not exceed the recommended dose.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.
Overdose Warning
In case of an overdose, symptoms may include nausea, vomiting, stomach pain, dizziness, and confusion. Seek immediate medical attention or contact emergency services if an overdose is suspected.
Side Effects
Common Side Effects
Nausea
Indigestion
Diarrhea
Less Common Side Effects
Dizziness
Rash
Serious Side Effects
Allergic reactions like swelling, itching, or difficulty breathing
Liver damage symptoms like yellowing of skin or eyes
When to Seek Immediate Medical Attention
If you experience severe allergic reactions or signs of liver damage.
Contraindications — Who Should Not Use This Medicine
- Allergy to NSAIDs — Patients with known allergies to NSAIDs should not use this medicine.
- Severe Liver or Kidney Disease — Not recommended for patients with severe hepatic or renal impairment.
- Active Peptic Ulcer — Should be avoided in patients with active ulcers.
Warnings & Precautions
Drug Interactions
Drug-Drug Interactions
Other NSAIDs
Anticoagulants like warfarin
Diuretics
Food Interactions
Can be taken with or without food.
Alcohol Interactions
Avoid alcohol as it may increase liver damage risk.
Disease Interactions
Peptic ulcer disease
Severe liver or kidney disease
Storage Instructions
Store at room temperature (15-25°C).
Keep away from moisture and light.
Keep out of reach of children.
Check the expiry date before use.
Expert Advice
Take the medicine exactly as prescribed by your doctor.
Do not exceed the recommended dose.
Inform your doctor about any other medications you are taking.
Avoid alcohol while using this medicine.
Monitor for any signs of allergic reactions.
Do not use if you have a history of severe liver or kidney disease.
Consult your doctor if symptoms persist or worsen.
Store the medicine properly to maintain its efficacy.
Report any unusual side effects to your healthcare provider.
Substitute Medicines
Same composition, different brands. Always consult your doctor before switching.
Sources
The information on this page about Acenate-SP Tablet has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.
- Manufacturer – Acenate-SP Tablet Prescribing Information and Product Monograph
- NHS – Aceclofenac: Uses, Side Effects, and More
- Mayo Clinic – Acetaminophen (Oral Route)
- MedlinePlus – Aceclofenac
- Drugs.com – Aceclofenac and Paracetamol