Acip-MR Tablet
Active Composition
About Acip-MR Tablet
Acip-MR Tablet is a combination medication containing Aceclofenac and Paracetamol. It is primarily used to relieve pain and inflammation associated with conditions such as arthritis, muscle pain, and dental pain. This medicine is suitable for adults and should be used under medical supervision. It works by reducing the production of certain chemicals in the body that cause pain and inflammation. Patients with a history of liver or kidney issues should consult their doctor before use.
Clinical Uses
- Osteoarthritis — A condition causing joint pain and stiffness.
- Rheumatoid Arthritis — An autoimmune disorder causing joint inflammation.
- Ankylosing Spondylitis — A type of arthritis affecting the spine.
- Muscle Pain — Pain due to muscle strain or injury.
Uses & Indications
Primary Uses
Relief of pain and inflammation in arthritis.
Management of muscle pain.
Secondary Uses
Relief of dental pain.
Off-label Uses
How It Works (Mechanism of Action)
Acip-MR Tablet works by combining the effects of Aceclofenac and Paracetamol. Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation by blocking the production of certain chemicals in the body. Paracetamol is an analgesic that helps in reducing pain and fever.
Scientifically, Aceclofenac inhibits the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins, compounds that mediate inflammation and pain. Paracetamol works centrally in the brain to increase the pain threshold and reduce fever by acting on the hypothalamic heat-regulating center.
Key Benefits
- Pain Relief — Helps in reducing pain from various conditions.
- Anti-inflammatory — Reduces swelling and inflammation in joints and muscles.
- Improved Mobility — Eases movement by reducing pain and stiffness.
How Long Does It Take to Work?
Initial improvement in pain relief can be observed within 1 to 2 hours after taking the tablet. For full therapeutic effects, it may take a few days of regular use. If there is no improvement in symptoms after a week, consult your doctor.
How to Use
Take the tablet by mouth with a glass of water.
It is best taken with food to avoid stomach upset.
Follow the dosage prescribed by your doctor.
Do not crush or chew the tablet.
Take it at the same time each day for the best results.
Dosage Guidelines
Adult Dose
Typically, one tablet twice a day or as prescribed by the doctor.
Pediatric Dose
Not recommended for children.
Elderly
Use with caution; dosage may need adjustment.
Administration Instructions
Swallow the tablet whole with water.
Take with or after food to minimize stomach irritation.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Overdose Warning
In case of overdose, symptoms may include nausea, vomiting, stomach pain, dizziness, or drowsiness. Seek immediate medical attention or contact a poison control center.
Side Effects
Common Side Effects
Nausea
Indigestion
Diarrhea
Less Common Side Effects
Dizziness
Rash
Serious Side Effects
Allergic reactions like swelling of face, lips, or throat
Severe stomach pain
Yellowing of skin or eyes (jaundice)
When to Seek Immediate Medical Attention
If you experience difficulty breathing or severe allergic reactions.
Contraindications — Who Should Not Use This Medicine
- Allergy to NSAIDs — Patients allergic to NSAIDs should not use this medicine.
- Severe Liver or Kidney Disease — Not recommended for patients with severe liver or kidney impairment.
- Peptic Ulcer — Patients with active peptic ulcer should avoid this medication.
Warnings & Precautions
Drug Interactions
Drug-Drug Interactions
Warfarin
Other NSAIDs
Diuretics
Food Interactions
Take with food to reduce stomach irritation.
Alcohol Interactions
Avoid alcohol to prevent liver damage.
Disease Interactions
Liver disease
Kidney disease
Storage Instructions
Store at room temperature (15-25°C).
Keep away from moisture and light.
Keep out of reach of children.
Check the expiry date before use.
Expert Advice
Take the medication exactly as prescribed by your doctor.
Do not exceed the recommended dose.
Inform your doctor about any other medications you are taking.
Report any unusual symptoms to your doctor immediately.
Do not use this medication if you have a history of allergic reactions to NSAIDs.
Regularly monitor liver and kidney function if using long-term.
Consult your doctor if you are pregnant or breastfeeding.
Avoid alcohol consumption while taking this medication.
Do not share your medication with others.
Substitute Medicines
Same composition, different brands. Always consult your doctor before switching.
Sources
The information on this page about Acip-MR Tablet has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.
- Manufacturer – Acip-MR Tablet Prescribing Information and Product Monograph
- NHS – Aceclofenac and Paracetamol
- Mayo Clinic – Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
- MedlinePlus – Aceclofenac
- Drugs.com – Aceclofenac and Paracetamol Information