Acloboot MR 100mg/325mg/250mg Tablet

by Boots Lifesciences Ltd · Tablet Schedule H
Generic Name Aceclofenac, Paracetamol
Drug Class Nonsteroidal Anti-inflammatory Drug (NSAID) and Analgesic
Route Oral
Habit Forming No
Prescription Required (Rx)
Strengths 100mg/325mg
MRP
₹85.50
strip of 10 tablets

About Acloboot MR 100mg/325mg/250mg Tablet

Acloboot MR 100mg/325mg/250mg Tablet is a combination medication used to relieve pain and inflammation. It contains Aceclofenac, a nonsteroidal anti-inflammatory drug (NSAID), and Paracetamol, a common pain reliever. This medicine is typically prescribed for conditions such as arthritis, muscle pain, and other inflammatory conditions. It is suitable for adults and should be taken as directed by a healthcare professional. Patients with a history of stomach ulcers, liver or kidney issues should consult their doctor before use.

Clinical Uses

  • Osteoarthritis — Relieves pain and inflammation in joints.
  • Rheumatoid Arthritis — Reduces joint pain and swelling.
  • Ankylosing Spondylitis — Eases stiffness and pain in the spine.

Uses & Indications

Primary Uses

Relief of pain and inflammation in arthritis.

Management of mild to moderate pain.

Secondary Uses

Relief from muscle pain.

Reduction of fever.

Off-label Uses

May be used for other types of pain as advised by a doctor.

How It Works (Mechanism of Action)

Acloboot MR works by combining the effects of aceclofenac and paracetamol. Aceclofenac reduces inflammation and pain by blocking the production of chemical messengers in the body that cause inflammation. Paracetamol works by inhibiting the production of prostaglandins in the brain, which helps to reduce pain and fever.

Scientifically, aceclofenac is a non-selective inhibitor of the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins. Paracetamol, on the other hand, is believed to inhibit COX-3 in the central nervous system, providing analgesic and antipyretic effects.

Key Benefits

  • Effective Pain Relief — Quickly reduces pain and discomfort.
  • Anti-inflammatory — Helps reduce swelling and inflammation.
  • Combination Therapy — Provides dual action with two active ingredients.

How Long Does It Take to Work?

Initial improvement in pain relief can typically be felt within 30 minutes to 1 hour after taking the tablet. Full therapeutic effects may take a few days of regular use. If there is no improvement in symptoms after a few days, or if symptoms worsen, consult a doctor.

How to Use

Take the tablet by mouth with a full glass of water.

Swallow the tablet whole; do not crush or chew it.

Take with or after food to minimize stomach upset.

Follow the dosage instructions provided by your doctor.

Do not exceed the recommended dose.

Dosage Guidelines

Adult Dose

Typically, one tablet taken 1-2 times daily as prescribed.

Pediatric Dose

Not recommended for children unless specifically prescribed by a doctor.

Elderly

May require dose adjustment; consult a doctor.

Administration Instructions

Take with food or milk to reduce gastrointestinal discomfort.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double the dose to catch up.

Overdose Warning

In case of overdose, symptoms may include nausea, vomiting, stomach pain, dizziness, or drowsiness. Seek immediate medical attention or contact poison control services.

Side Effects

Common Side Effects

Stomach pain

Nausea

Dizziness

Less Common Side Effects

Rash

Heartburn

Serious Side Effects

Severe allergic reactions

Swelling of the face or throat

Severe stomach pain

When to Seek Immediate Medical Attention

If you experience difficulty breathing or swelling of the face and throat.

Contraindications — Who Should Not Use This Medicine

  • Allergy to NSAIDs — Patients with known allergies should avoid use.
  • Severe Liver or Kidney Disease — May worsen these conditions.
  • Active Peptic Ulcer — Can increase risk of bleeding.

Warnings & Precautions

🤰 Pregnancy
Pregnancy Category C. This medication should be used during pregnancy only if clearly needed and prescribed by a doctor. It is not recommended during the last trimester.
🤱 Breastfeeding
Use with caution while breastfeeding. Consult your doctor before use as it may pass into breast milk in small amounts.
👶 Children
Not recommended for children unless specifically prescribed by a healthcare provider. Dosage adjustments are necessary.
🧓 Elderly
Elderly patients may be more sensitive to the side effects of this medication. Dose adjustments may be required.
🫘 Kidney Disease
Use with caution in patients with renal impairment. Dose adjustments may be necessary.
🫁 Liver Disease
Use with caution in patients with liver impairment. Dose adjustments may be necessary.
💉 Diabetes
Diabetic patients should monitor their blood sugar levels as this medication may affect glucose control.
🍷 Alcohol
Avoid alcohol while taking this medication as it can increase the risk of liver damage.
🚗 Driving
This medication may cause dizziness. Avoid driving or operating heavy machinery if you feel dizzy.

Drug Interactions

Drug-Drug Interactions

Aspirin

Warfarin

Other NSAIDs

Food Interactions

Take with food to reduce stomach irritation.

Alcohol Interactions

Avoid alcohol to prevent increased risk of liver damage.

Disease Interactions

Peptic Ulcer Disease

Liver Disease

Kidney Disease

Storage Instructions

Store at room temperature (15-30°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check expiry date before use.

Expert Advice

Clinical Tips

Complete the full course as prescribed by your doctor.

Do not share your medication with others.

Inform your doctor of all medications you are taking.

Report any unusual symptoms to your doctor immediately.

Do not take more than the recommended dose.

Take with food to reduce stomach upset.

Monitor for signs of allergic reactions.

Keep hydrated while taking this medication.

Consult your doctor before taking if you have liver or kidney issues.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

The information on this page about Acloboot MR 100mg/325mg/250mg Tablet has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.

  1. Manufacturer – Acloboot MR 100mg/325mg/250mg Tablet Prescribing Information and Product Monograph
  2. NHSAceclofenac: Uses, Side Effects, and Dosage
  3. Mayo ClinicAcetaminophen (Paracetamol) Overview
  4. MedlinePlusAceclofenac and Paracetamol Combination
  5. Drugs.comAceclofenac and Paracetamol Information
Last Updated15 Jun 2026
Content Generated15 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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