Acloflam SP 100mg/325mg/15mg Tablet

by Endolabs Ltd · Tablet Schedule H
Generic Name Aceclofenac, Paracetamol, Serratiopeptidase
Drug Class Nonsteroidal Anti-inflammatory Drug (NSAID) and Analgesic
Route Oral
Habit Forming No
Prescription Required (Rx)
Strengths 100mg/325mg/15mg
MRP
₹75.00
strip of 10 tablets

About Acloflam SP 100mg/325mg/15mg Tablet

Acloflam SP 100mg/325mg/15mg Tablet is a combination medication used to relieve pain and inflammation. It contains Aceclofenac, which is a nonsteroidal anti-inflammatory drug (NSAID), Paracetamol, an analgesic and antipyretic, and Serratiopeptidase, an enzyme that helps reduce inflammation. This medication is commonly used to treat conditions such as arthritis, muscle pain, and dental pain. It is suitable for adults and should be taken as prescribed by a healthcare professional. It is important to follow the dosage instructions carefully to avoid potential side effects.

Clinical Uses

  • Arthritis — Reduces pain and inflammation in joints.
  • Muscle Pain — Alleviates pain and swelling in muscles.
  • Dental Pain — Provides relief from pain after dental procedures.

Uses & Indications

Primary Uses

Relief of pain and inflammation in arthritis.

Management of muscle pain.

Reduction of dental pain.

Secondary Uses

Relief from postoperative pain.

Management of mild to moderate pain from other causes.

Off-label Uses

May be used for other types of pain as advised by a doctor.

How It Works (Mechanism of Action)

Acloflam SP works by combining the effects of its three active ingredients. Aceclofenac reduces inflammation and pain by inhibiting the production of certain chemicals in the body. Paracetamol helps to relieve pain and reduce fever. Serratiopeptidase aids in breaking down proteins at the site of inflammation, reducing swelling and promoting healing.

Scientifically, Aceclofenac is a selective inhibitor of cyclooxygenase-2 (COX-2), which decreases the synthesis of prostaglandins involved in inflammation and pain. Paracetamol works centrally in the brain to inhibit the synthesis of prostaglandins, providing analgesic and antipyretic effects. Serratiopeptidase is a proteolytic enzyme that breaks down inflammatory proteins, aiding in reducing edema and promoting tissue repair.

Key Benefits

  • Pain Relief — Effectively reduces pain from various conditions.
  • Anti-inflammatory — Helps decrease inflammation and swelling.
  • Improved Mobility — Reduces joint stiffness, improving movement.

How Long Does It Take to Work?

Initial improvement in pain and inflammation can be noticed within 30 minutes to 1 hour after taking the tablet. Full therapeutic effects may take a few days of regular use. If there is no improvement in symptoms after a few days, or if symptoms worsen, it is important to consult a doctor.

How to Use

Take the tablet orally with a glass of water.

It is best taken with food to minimize stomach upset.

Follow your doctor's instructions on the dosage and duration.

Do not crush or chew the tablet; swallow it whole.

Take it at the same time each day for best results.

Dosage Guidelines

Adult Dose

Typically, one tablet taken 1-2 times daily, as prescribed by a doctor.

Pediatric Dose

Not recommended for children under 18 years unless prescribed by a doctor.

Elderly

Use with caution; dosage may need adjustment based on health status.

Administration Instructions

Take with food to reduce gastrointestinal discomfort.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Overdose Warning

In case of overdose, symptoms may include nausea, vomiting, stomach pain, dizziness, or drowsiness. Seek immediate medical attention or contact a poison control center if an overdose is suspected.

Side Effects

Common Side Effects

Nausea

Indigestion

Diarrhea

Less Common Side Effects

Dizziness

Rash

Headache

Serious Side Effects

Allergic reactions like swelling, itching, or rash

Severe stomach pain

Yellowing of the skin or eyes (jaundice)

When to Seek Immediate Medical Attention

If you experience difficulty breathing or swelling of the face, lips, tongue, or throat.

Contraindications — Who Should Not Use This Medicine

  • Allergy to NSAIDs — Patients allergic to NSAIDs should not use this medication.
  • Severe Liver or Kidney Disease — Not recommended for patients with severe organ impairment.
  • Active Peptic Ulcer — May worsen ulcer conditions.

Warnings & Precautions

🤰 Pregnancy
Pregnancy Category C. This medication should be used during pregnancy only if clearly needed and prescribed by a doctor. It is important to weigh the potential benefits against the risks.
🤱 Breastfeeding
It is not recommended to use this medication while breastfeeding unless advised by a healthcare provider. Discuss potential risks and benefits with your doctor.
👶 Children
This medication is not recommended for use in children under 18 years of age unless specifically prescribed by a healthcare provider.
🧓 Elderly
Elderly patients may be more sensitive to the side effects of this medication. Dose adjustments may be necessary based on individual health conditions.
🫘 Kidney Disease
Patients with kidney impairment should use this medication with caution. Dose adjustments may be necessary.
🫁 Liver Disease
Patients with liver impairment should use this medication with caution. Dose adjustments may be necessary.
💉 Diabetes
Diabetic patients should use this medication with caution and monitor blood sugar levels regularly.
🍷 Alcohol
Avoid alcohol consumption while taking this medication as it may increase the risk of liver damage and stomach bleeding.
🚗 Driving
This medication may cause dizziness; avoid driving or operating heavy machinery if you feel drowsy.

Drug Interactions

Drug-Drug Interactions

Avoid using with other NSAIDs or blood thinners like warfarin.

May interact with certain blood pressure medications.

Food Interactions

Take with food to reduce stomach irritation.

Alcohol Interactions

Avoid alcohol to prevent increased risk of liver damage.

Disease Interactions

Use with caution in patients with liver or kidney disease.

Storage Instructions

Store at room temperature (15-30°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check the expiry date before use.

Expert Advice

Clinical Tips

Complete the full course as prescribed by your doctor.

Take with food to minimize stomach upset.

Do not share your medication with others.

Avoid alcohol while taking this medication.

Inform your doctor of any other medications you are taking.

Report any unusual symptoms to your doctor immediately.

Do not take more than the recommended dose.

Keep the medication in its original packaging.

Consult your doctor before stopping the medication.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

The information on this page about Acloflam SP 100mg/325mg/15mg Tablet has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.

  1. Manufacturer – Acloflam SP 100mg/325mg/15mg Tablet Prescribing Information and Product Monograph
  2. NHSAceclofenac: Uses, Side Effects, and More
  3. Mayo ClinicNonsteroidal Anti-Inflammatory Drugs (NSAIDs)
  4. MedlinePlusParacetamol (Acetaminophen): MedlinePlus Drug Information
  5. Drugs.comAceclofenac and Paracetamol Tablets
Last Updated15 Jun 2026
Content Generated15 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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