Aclosara SP 100mg/325mg/15mg Tablet

by Sara Remedies · Tablet Schedule H
Generic Name Aceclofenac, Paracetamol, Serratiopeptidase
Drug Class Nonsteroidal Anti-inflammatory Drug (NSAID) and Analgesic
Route Oral
Habit Forming No
Prescription Required (Rx)
Strengths 100mg/325mg/15mg
MRP
₹70.00
strip of 10 tablets

About Aclosara SP 100mg/325mg/15mg Tablet

Aclosara SP 100mg/325mg/15mg Tablet is a combination medication used to relieve pain and inflammation. It contains Aceclofenac, Paracetamol, and Serratiopeptidase. Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation. Paracetamol is an analgesic that helps reduce fever and pain. Serratiopeptidase is an enzyme that helps reduce swelling. This medication is typically used for conditions such as arthritis, muscle pain, and post-surgical pain. It should be used under medical supervision, especially in patients with liver or kidney issues.

Clinical Uses

  • Arthritis — Helps reduce inflammation and pain in joints.
  • Muscle Pain — Relieves pain and swelling in muscles.
  • Post-surgical Pain — Manages pain and inflammation after surgery.

Uses & Indications

Primary Uses

Relief of pain and inflammation in arthritis.

Management of muscle pain.

Reduction of post-surgical pain and swelling.

Secondary Uses

Relief of dental pain.

Management of headache and migraine.

Off-label Uses

May be used for other types of pain as advised by a doctor.

How It Works (Mechanism of Action)

Aclosara SP works by combining the effects of its three active ingredients. Aceclofenac reduces pain and inflammation by blocking the production of certain chemical messengers in the body. Paracetamol works by inhibiting the production of prostaglandins in the brain, which helps reduce pain and fever. Serratiopeptidase helps break down proteins involved in inflammation, thereby reducing swelling and improving tissue repair.

Scientifically, Aceclofenac inhibits cyclooxygenase (COX) enzymes, reducing the synthesis of prostaglandins. Paracetamol's exact mechanism is not fully understood but is believed to involve central inhibition of COX. Serratiopeptidase is a proteolytic enzyme that breaks down inflammatory proteins, aiding in the reduction of inflammation and edema.

Key Benefits

  • Pain Relief — Provides effective relief from various types of pain.
  • Anti-inflammatory — Reduces inflammation and swelling.
  • Fever Reduction — Lowers fever associated with pain and inflammation.

How Long Does It Take to Work?

Initial improvement in pain and inflammation can be noticed within a few hours of taking the tablet. Full therapeutic effects may take a few days of regular use. If there is no improvement in symptoms after a week, consult your doctor.

How to Use

Take the tablet by mouth with a full glass of water.

Swallow the tablet whole, do not crush or chew it.

Take it with or after food to avoid stomach upset.

Follow the dosage prescribed by your doctor.

Do not exceed the recommended dose.

Dosage Guidelines

Adult Dose

Typically, one tablet taken 1-2 times daily as directed by a physician.

Pediatric Dose

Not recommended for children without medical advice.

Elderly

Use with caution; dose adjustment may be necessary.

Administration Instructions

Take with food to minimize gastrointestinal discomfort.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Overdose Warning

In case of overdose, symptoms may include nausea, vomiting, stomach pain, dizziness, and confusion. Seek immediate medical attention or contact poison control. Do not wait for symptoms to appear.

Side Effects

Common Side Effects

Nausea

Indigestion

Diarrhea

Less Common Side Effects

Dizziness

Rash

Serious Side Effects

Allergic reactions like swelling of the face, lips, or throat

Severe stomach pain

Yellowing of the skin or eyes

When to Seek Immediate Medical Attention

If you experience difficulty breathing or severe allergic reactions.

Contraindications — Who Should Not Use This Medicine

  • Allergy — Do not use if allergic to Aceclofenac, Paracetamol, or Serratiopeptidase.
  • Severe Liver Disease — Not recommended due to potential liver damage.
  • Severe Kidney Disease — Use may worsen kidney function.
  • Peptic Ulcer — May exacerbate ulcer symptoms.

Warnings & Precautions

🤰 Pregnancy
Pregnancy Category C. This medication should be used during pregnancy only if clearly needed and prescribed by a doctor. It is important to discuss potential risks and benefits with your healthcare provider.
🤱 Breastfeeding
It is not known if this medication passes into breast milk. Consult your doctor before using this medication while breastfeeding to weigh potential risks and benefits.
👶 Children
This medication is not recommended for use in children without medical advice. Always consult a pediatrician before administering to children.
🧓 Elderly
Elderly patients may be more sensitive to the effects of this medication. Dose adjustments may be necessary, and it should be used with caution.
🫘 Kidney Disease
Patients with renal impairment should use this medication with caution. Dose adjustment may be required based on kidney function.
🫁 Liver Disease
Use with caution in patients with liver impairment. Dose adjustment may be necessary, and liver function should be monitored regularly.
💉 Diabetes
Diabetic patients should use this medication with caution as it may affect blood sugar levels. Regular monitoring is advised.
🍷 Alcohol
Avoid alcohol while taking this medication as it may increase the risk of liver damage and gastrointestinal bleeding.
🚗 Driving
This medication may cause dizziness. Avoid driving or operating heavy machinery until you know how it affects you.

Drug Interactions

Drug-Drug Interactions

Warfarin

Other NSAIDs

Antihypertensives

Food Interactions

Take with food to reduce stomach upset.

Alcohol Interactions

Avoid alcohol to prevent increased risk of liver damage.

Disease Interactions

Liver disease

Kidney disease

Peptic ulcer disease

Storage Instructions

Store at room temperature (15-30°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check expiry date before use.

Expert Advice

Clinical Tips

Complete the full course as prescribed by your doctor.

Do not share your medication with others.

Avoid taking other NSAIDs concurrently.

Inform your doctor of any other medications you are taking.

Monitor liver function regularly if used long-term.

Report any unusual symptoms to your doctor promptly.

Do not stop taking the medication abruptly without consulting your doctor.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

The information on this page about Aclosara SP 100mg/325mg/15mg Tablet has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.

  1. Manufacturer – Aclosara SP 100mg/325mg/15mg Tablet Prescribing Information and Product Monograph
  2. NHSAceclofenac: medicine to treat pain and inflammation
  3. Mayo ClinicNonsteroidal Anti-inflammatory Drugs (NSAIDs)
  4. MedlinePlusAceclofenac
  5. Drugs.comAceclofenac
Last Updated15 Jun 2026
Content Generated15 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
Scroll to Top