Asirest-MR Tablet
Active Composition
About Asirest-MR Tablet
Asirest-MR Tablet is a combination medication containing Aceclofenac and Paracetamol. It is primarily used to relieve pain and inflammation in conditions such as arthritis, muscle pain, and dental pain. This medication is suitable for adults and should be used under medical supervision. It works by reducing the production of chemicals in the body that cause pain and inflammation. Patients with a history of allergies to NSAIDs or paracetamol should avoid using this medication.
Clinical Uses
- Arthritis — Reduces pain and inflammation in joint disorders.
- Muscle Pain — Alleviates discomfort from muscle injuries or strains.
- Dental Pain — Provides relief from pain after dental procedures.
Uses & Indications
Primary Uses
Relief of pain and inflammation in arthritis.
Management of muscle pain and strains.
Alleviation of dental pain.
Secondary Uses
Relief from headache and back pain.
Off-label Uses
May be used for other types of pain as prescribed by a doctor.
How It Works (Mechanism of Action)
The Asirest-MR Tablet works by combining two active ingredients: Aceclofenac and Paracetamol. Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation by blocking the production of certain chemical messengers in the body. Paracetamol, also known as acetaminophen, works by inhibiting the production of prostaglandins in the brain, which helps to reduce pain and fever.
Scientifically, Aceclofenac inhibits the cyclooxygenase (COX) enzymes, which are involved in the synthesis of prostaglandins, leading to reduced inflammation and pain. Paracetamol acts centrally in the brain to block the production of prostaglandins, providing analgesic and antipyretic effects without significant anti-inflammatory activity.
Key Benefits
- Pain Relief — Effectively reduces pain in various conditions.
- Anti-inflammatory — Decreases inflammation in affected areas.
- Improves Mobility — Helps improve movement by reducing joint pain.
How Long Does It Take to Work?
Initial pain relief from Asirest-MR Tablet can be expected within 30 minutes to 1 hour after taking the dose. Full therapeutic effects for inflammation may take a few days of regular use. If there is no improvement in symptoms after a few days, or if symptoms worsen, consult a doctor.
How to Use
Take the tablet by mouth with a full glass of water.
Swallow the tablet whole; do not crush or chew.
Take with or after food to minimize stomach upset.
Follow the dosage instructions provided by your doctor.
Do not exceed the recommended dose.
Dosage Guidelines
Adult Dose
Typically, one tablet taken 1-2 times daily, as prescribed by a doctor.
Pediatric Dose
Not recommended for children without medical advice.
Elderly
Use with caution and under medical supervision.
Administration Instructions
Take with food to reduce gastrointestinal discomfort.
Missed Dose
If you miss a dose of Asirest-MR Tablet, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Overdose Warning
In case of an overdose, symptoms may include nausea, vomiting, stomach pain, dizziness, or drowsiness. Seek immediate medical attention or contact emergency services or poison control for guidance.
Side Effects
Common Side Effects
Nausea
Indigestion
Dizziness
Less Common Side Effects
Diarrhea
Constipation
Serious Side Effects
Allergic reactions such as rash, itching, or swelling
Severe stomach pain
Yellowing of the skin or eyes (jaundice)
When to Seek Immediate Medical Attention
Difficulty breathing
Swelling of the face, lips, or throat
Severe rash or hives
Contraindications — Who Should Not Use This Medicine
- Allergy to NSAIDs or Paracetamol — May cause severe allergic reactions.
- Severe Liver Impairment — Risk of liver damage.
- Severe Kidney Impairment — Risk of worsening kidney function.
- Active Peptic Ulcer — May exacerbate ulcer symptoms.
Warnings & Precautions
Drug Interactions
Drug-Drug Interactions
Other NSAIDs
Blood thinners like warfarin
Certain blood pressure medications
Food Interactions
Take with food to reduce stomach upset.
Alcohol Interactions
Avoid alcohol to prevent liver damage.
Disease Interactions
Liver disease
Kidney disease
Asthma
Storage Instructions
Store at room temperature (15-30°C).
Keep away from moisture.
Protect from light.
Keep out of reach of children.
Check expiry date before use.
Expert Advice
Complete the full course as prescribed by your doctor.
Do not share your medication with others.
Inform your doctor of all medications you are taking.
Monitor for any signs of allergic reactions.
Do not take more than the recommended dose.
Consult your doctor if symptoms persist or worsen.
Report any unusual side effects to your healthcare provider.
Substitute Medicines
Same composition, different brands. Always consult your doctor before switching.
Sources
The information on this page about Asirest-MR Tablet has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.
- Manufacturer – Asirest-MR Tablet Prescribing Information and Product Monograph
- NHS – Aceclofenac and Paracetamol: Uses, Side Effects, and More
- Mayo Clinic – Nonsteroidal Anti-inflammatory Drugs (NSAIDs)
- MedlinePlus – Aceclofenac and Paracetamol: Drug Information
- Drugs.com – Aceclofenac and Paracetamol: Side Effects and Dosage