Astofen SP 100mg/325mg/15mg Tablet

Astofen SP 100mg/325mg/15mg Tablet is a combination medicine used to relieve pain and inflammation in conditions like arthritis, muscle pain, and dental pain. It contains Aceclofenac, which is a nonsteroidal anti-inflammatory drug (NSAID), and Paracetamol, which is an analgesic. This medication is suitable for adults and should be taken as prescribed by a healthcare provider. It is important to follow the dosage instructions carefully to avoid side effects.

• Arthritis — Helps reduce pain and inflammation in joints.
• Muscle Pain — Provides relief from muscle aches and pains.
• Dental Pain — Alleviates pain after dental procedures.

Primary Uses

Relief from arthritis pain and inflammation.

Management of muscle pain.

Reduction of dental pain.

Secondary Uses

May be used for other types of mild to moderate pain as advised by a doctor.

Off-label Uses

Not typically used for off-label purposes.

Astofen SP works by combining the effects of Aceclofenac and Paracetamol. Aceclofenac reduces pain and inflammation by blocking the production of certain chemical messengers in the body. Paracetamol works by inhibiting the production of prostaglandins in the brain, which helps to reduce pain and fever.

Scientifically, Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins. Paracetamol primarily acts on the central nervous system to reduce pain and fever, although its exact mechanism is not fully understood.

• Pain Relief — Effectively reduces pain in various conditions.
• Anti-inflammatory — Decreases inflammation, improving mobility and comfort.
• Combination Therapy — Provides dual action for better pain management.

Initial improvement in pain and inflammation can be observed within 30 minutes to 1 hour after taking the tablet. Full therapeutic effects may take several days of consistent use. If there is no improvement in symptoms after a few days, consult your doctor.

Take the tablet with a full glass of water.

Swallow the tablet whole; do not crush or chew it.

Take the medicine with or after food to avoid stomach upset.

Follow the prescribed dosage schedule strictly.

Do not exceed the recommended dose.

Adult Dose

Typically, one tablet taken 1-2 times daily as prescribed by a doctor.

Pediatric Dose

Not recommended for children.

Elderly

Use with caution; dosage may need adjustment based on health condition.

Administration Instructions

Take with food to minimize gastrointestinal discomfort.

Common Side Effects

Nausea

Indigestion

Dizziness

Less Common Side Effects

Rash

Diarrhea

Serious Side Effects

Allergic reactions like swelling of the face or throat

Severe stomach pain

When to Seek Immediate Medical Attention

If you experience difficulty breathing or severe allergic reactions.

• Allergy to NSAIDs — Patients with known allergies to NSAIDs should not use this medicine.
• Severe Liver Disease — Not recommended for patients with severe liver impairment.
• Active Peptic Ulcer — Should be avoided in patients with active ulcers.

Drug-Drug Interactions

Aspirin

Warfarin

Other NSAIDs

Food Interactions

Take with food to reduce stomach upset.

Alcohol Interactions

Avoid alcohol to prevent increased risk of liver damage.

Disease Interactions

Peptic ulcer disease

Severe liver impairment

Store at room temperature (15-25°C).

Keep away from moisture and light.

Keep out of reach of children.

Check the expiry date before use.