Axipar SP Tablet

Axipar SP Tablet is a combination medication containing Aceclofenac and Paracetamol. It is primarily used to relieve pain and inflammation in conditions such as arthritis, muscle pain, and dental pain. Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that reduces inflammation and pain, while Paracetamol is an analgesic that helps alleviate pain and reduce fever. This medication is suitable for adults and should be used under the guidance of a healthcare professional.

• Osteoarthritis — A degenerative joint disease causing pain and stiffness.
• Rheumatoid Arthritis — An autoimmune disorder causing joint inflammation and pain.
• Musculoskeletal Pain — Pain affecting muscles, ligaments, tendons, and bones.
• Dental Pain — Pain associated with dental conditions or procedures.

Primary Uses

Pain relief in osteoarthritis and rheumatoid arthritis.

Reduction of inflammation in musculoskeletal disorders.

Secondary Uses

Relief of dental pain.

Management of mild to moderate pain and fever.

Off-label Uses

Axipar SP Tablet works by combining the effects of Aceclofenac and Paracetamol. Aceclofenac reduces the production of prostaglandins, chemicals in the body that cause pain and inflammation. Paracetamol works centrally in the brain to relieve pain and reduce fever.

Scientifically, Aceclofenac inhibits the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins. Paracetamol is believed to inhibit COX enzymes in the brain, providing analgesic and antipyretic effects without significant anti-inflammatory action.

• Effective Pain Relief — Provides relief from various types of pain including joint and muscle pain.
• Anti-inflammatory Action — Reduces inflammation associated with arthritis and other conditions.
• Fever Reduction — Helps lower fever due to its antipyretic properties.

Initial improvement in pain relief can be observed within 30 minutes to 1 hour after taking the tablet. Full therapeutic effects may take a few days of consistent use. If there is no improvement in symptoms after a few days, consult your doctor.

Take the tablet orally with a glass of water.

Swallow the tablet whole; do not crush or chew.

Take with or after food to minimize stomach upset.

Follow the dosage prescribed by your doctor.

Do not exceed the recommended dose.

Adult Dose

Typically, one tablet twice daily.

Pediatric Dose

Not recommended for children.

Elderly

Use with caution; dose adjustment may be necessary.

Administration Instructions

Take with food to reduce gastrointestinal side effects.

Common Side Effects

Stomach pain

Nausea

Diarrhea

Less Common Side Effects

Dizziness

Rash

Serious Side Effects

Allergic reactions such as swelling of the face or throat

Severe stomach pain

Yellowing of the skin or eyes

When to Seek Immediate Medical Attention

If you experience difficulty breathing or swelling of the face, lips, tongue, or throat.

• Allergy to NSAIDs — Patients with known hypersensitivity should avoid use.
• Severe Liver or Kidney Disease — Use may worsen these conditions.
• History of Peptic Ulcers — Risk of gastrointestinal bleeding.

Drug-Drug Interactions

• Warfarin — May increase bleeding risk.
• Aspirin — May increase side effects.
• Diuretics — May reduce effectiveness.

Food Interactions

Take with food to reduce stomach upset.

Alcohol Interactions

Avoid alcohol to prevent liver damage.

Disease Interactions

• Peptic Ulcer Disease — May worsen condition.
• Liver Disease — Use with caution.

Store at room temperature (15-30°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check expiry date before use.