Jefrest 200mg Tablet

Jefrest 200mg Tablet contains Aceclofenac, which is a nonsteroidal anti-inflammatory drug (NSAID). It is primarily used to relieve pain and inflammation associated with conditions like arthritis, ankylosing spondylitis, and other musculoskeletal disorders. This medicine is suitable for adults and should be taken as prescribed by a healthcare professional. It helps in reducing pain, swelling, and stiffness in the joints, thereby improving mobility and quality of life.

• Osteoarthritis — A condition causing joint pain and stiffness.
• Rheumatoid Arthritis — An autoimmune disorder causing joint inflammation.
• Ankylosing Spondylitis — A type of arthritis affecting the spine.

Primary Uses

Relief of pain and inflammation in osteoarthritis.

Treatment of rheumatoid arthritis symptoms.

Management of ankylosing spondylitis.

Secondary Uses

Relief of mild to moderate pain from other musculoskeletal disorders.

Off-label Uses

Aceclofenac works by blocking the action of certain chemical messengers in the body that cause pain and inflammation. This helps in reducing symptoms like swelling, pain, and stiffness.

Scientifically, Aceclofenac inhibits the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins. Prostaglandins are compounds that mediate inflammation and pain. By inhibiting COX, Aceclofenac decreases the production of prostaglandins, thus exerting its anti-inflammatory and analgesic effects.

• Pain Relief — Helps in reducing pain associated with arthritis and other conditions.
• Anti-inflammatory — Reduces inflammation in the joints and muscles.
• Improved Mobility — Alleviates stiffness, enhancing movement and flexibility.

Initial improvement in pain and inflammation may be noticed within a few hours of taking the medication. However, full therapeutic effects may take several days to become apparent. If there is no improvement in symptoms after a week of regular use, consult your doctor.

Take the tablet by mouth with a glass of water.

Swallow the tablet whole; do not crush or chew it.

Take it with or after food to minimize stomach upset.

Follow the dosage instructions provided by your healthcare provider.

Do not exceed the recommended dose.

Adult Dose

Typically, one 200mg tablet once or twice daily as prescribed.

Pediatric Dose

Not recommended for children.

Elderly

Use with caution; dose adjustment may be necessary.

Administration Instructions

Take with food to reduce gastrointestinal side effects.

Common Side Effects

Stomach pain

Nausea

Indigestion

Less Common Side Effects

Dizziness

Rash

Serious Side Effects

Severe allergic reactions

Bleeding or ulcers in the stomach

When to Seek Immediate Medical Attention

Signs of an allergic reaction such as swelling of the face, lips, or throat.

Severe stomach pain or bloody stools.

• Allergy to Aceclofenac — Patients with known hypersensitivity should not use this medicine.
• Active Peptic Ulcer — May exacerbate ulcer conditions.
• Severe Heart Failure — Can worsen heart conditions.

Drug-Drug Interactions

Warfarin

Other NSAIDs

Diuretics

Food Interactions

Take with food to reduce stomach irritation.

Alcohol Interactions

Avoid alcohol to prevent increased risk of gastrointestinal bleeding.

Disease Interactions

Peptic Ulcer Disease

Heart Disease

Kidney Disease

Store at room temperature (15-25°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check the expiry date before use.