Neptol P 100mg/325mg Tablet

by Suncruz Pharmaceuticals · Tablet Rx
Generic Name Paracetamol and Nimesulide
Drug Class Non-steroidal anti-inflammatory drug (NSAID) and analgesic
Route Oral
Habit Forming No
Prescription Required (Rx)
Strengths 100mg/325mg
MRP
₹31.50
strip of 10 tablets

About Neptol P 100mg/325mg Tablet

Neptol P 100mg/325mg Tablet is a combination medication that contains Paracetamol and Nimesulide. It is used to relieve pain and reduce fever. This medicine is suitable for adults and children over 12 years old who need effective pain management for conditions like headaches, muscle pain, or arthritis. Always use this medication under the guidance of a healthcare professional to ensure safety and effectiveness.

Clinical Uses

  • Fever — Helps reduce high body temperature.
  • Headache — Provides relief from mild to moderate headaches.
  • Muscle Pain — Alleviates discomfort from muscle strains and injuries.
  • Arthritis — Reduces pain and inflammation in joint conditions.

Uses & Indications

Primary Uses

  • Pain Relief — Effective for managing various types of pain.
  • Fever Reduction — Helps lower fever in adults and adolescents.

Secondary Uses

  • Inflammation Control — Reduces swelling and discomfort associated with inflammation.

Off-label Uses

  • Menstrual Pain — May be used to relieve menstrual cramps.

How It Works (Mechanism of Action)

Neptol P works by blocking the production of certain chemicals in the body that cause pain and inflammation. Paracetamol reduces pain and fever, while Nimesulide helps decrease inflammation and swelling.

The scientific mechanism involves the inhibition of cyclooxygenase (COX) enzymes, which play a key role in the synthesis of prostaglandins. Prostaglandins are responsible for pain and inflammation. By reducing their production, Neptol P effectively alleviates discomfort and lowers fever.

Key Benefits

  • Fast Acting — Starts working quickly to relieve pain and fever.
  • Dual Action — Combines two effective ingredients for better results.
  • Convenient Form — Easy to take as a tablet.

How Long Does It Take to Work?

You may start to feel relief within 30 minutes after taking Neptol P. The full effect can usually be seen within 1 to 2 hours. If your symptoms do not improve after 3 days, you should consult your doctor.

How to Use

Take the tablet with a full glass of water.

Follow the dosage instructions provided by your doctor.

Do not crush or chew the tablet; swallow it whole.

Take it with food if you experience stomach upset.

Do not exceed the recommended dose.

Dosage Guidelines

Adult Dose

  • 1 tablet every 8 to 12 hours as needed, not exceeding 3 tablets in 24 hours.

Pediatric Dose

Not recommended for children under 12 years old without a doctor's advice.

Elderly

Use with caution; consult a doctor for appropriate dosing.

Administration Instructions

Take with or without food, but preferably with food to minimize stomach upset.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time.

Overdose Warning

Taking too much Neptol P can lead to serious health issues. Symptoms of overdose may include nausea, vomiting, loss of appetite, confusion, and jaundice. If you suspect an overdose, seek emergency medical help immediately or contact poison control.

Side Effects

Common Side Effects

Nausea

Stomach pain

Dizziness

Less Common Side Effects

Rash

Itching

Serious Side Effects

Liver damage

Severe allergic reactions

When to Seek Immediate Medical Attention

If you experience symptoms like difficulty breathing, swelling of the face or throat, or severe abdominal pain, seek medical help right away.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Nimesulide or Paracetamol — Risk of severe allergic reactions.
  • Severe Liver Disease — Increased risk of liver damage.
  • Pregnancy — Should be avoided unless prescribed by a doctor.

Warnings & Precautions

🤰 Pregnancy
Neptol P is generally not recommended during pregnancy, especially in the third trimester. Always consult your doctor before using any medication during pregnancy.
🤱 Breastfeeding
Paracetamol is considered safe during breastfeeding, but Nimesulide may not be. Consult your healthcare provider before taking this medication while breastfeeding.
👶 Children
Neptol P is not recommended for children under 12 years old without a doctor's advice. Dosage for children should always be determined by a healthcare professional.
🧓 Elderly
Elderly patients should use Neptol P with caution. Dosage may need to be adjusted based on individual health conditions.
🫘 Kidney Disease
Patients with kidney impairment should use Neptol P cautiously. Dose adjustments may be necessary depending on the severity of the condition.
🫁 Liver Disease
Patients with liver impairment should avoid using Neptol P, as it may increase the risk of liver damage. Always consult a doctor before use.
🍷 Alcohol
Avoid consuming alcohol while taking Neptol P, as it may increase the risk of liver damage.
🚗 Driving
Neptol P may cause dizziness in some individuals; use caution when driving or operating machinery.

Drug Interactions

Drug-Drug Interactions

Avoid using with other NSAIDs

Be cautious with anticoagulants

Food Interactions

No specific food interactions, but taking it with food may reduce stomach upset.

Alcohol Interactions

Alcohol can increase the risk of liver damage when taken with Neptol P.

Disease Interactions

Use with caution in patients with liver or kidney disease.

Storage Instructions

Store at room temperature (15-30°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check expiry date before use.

Expert Advice

Clinical Tips

Always follow the prescribed dosage.

Do not take for longer than recommended.

Stay hydrated while taking this medication.

Inform your doctor about any other medications you are taking.

Do not share your medication with others.

Keep track of your symptoms and report any changes to your doctor.

Consult your doctor if symptoms persist or worsen.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

Last Updated24 Jun 2026
Content Generated24 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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