Nimfe Plus 100mg/325mg Tablet

by Elixir Pharmacon · Tablet Rx
Generic Name Paracetamol and Nimesulide
Drug Class Non-steroidal anti-inflammatory drug (NSAID) and analgesic
Route Oral
Habit Forming No
Prescription Required (Rx)
Strengths 100mg/325mg
MRP
₹45.00
strip of 10 tablets

About Nimfe Plus 100mg/325mg Tablet

Nimfe Plus 100mg/325mg Tablet is a combination medication that contains Paracetamol and Nimesulide. It is used to relieve pain and reduce fever. This medicine is often prescribed for conditions such as headaches, muscle pain, and arthritis. It is important to follow your doctor's instructions when using this medication to ensure safety and effectiveness.

Clinical Uses

  • Headache — Relief from tension or migraine headaches.
  • Muscle Pain — Alleviation of pain due to muscle strain or injury.
  • Arthritis — Reduction of pain and inflammation in joint disorders.
  • Fever — Lowering of elevated body temperature.

Uses & Indications

Primary Uses

  • Pain Relief — Effective for various types of pain including headaches and muscle pain.
  • Fever Reduction — Helps in lowering fever associated with infections.

Secondary Uses

  • Arthritis Management — Used to manage pain and inflammation in arthritis.

How It Works (Mechanism of Action)

Nimfe Plus works by blocking the production of certain chemicals in the body that cause pain and inflammation. Paracetamol mainly acts in the brain to reduce pain and fever, while Nimesulide works at the site of inflammation to decrease swelling and discomfort.

The scientific mechanism involves the inhibition of cyclooxygenase (COX) enzymes, which are responsible for the synthesis of prostaglandins. Prostaglandins are chemicals that promote inflammation, pain, and fever. By reducing their production, Nimfe Plus effectively alleviates these symptoms.

Key Benefits

  • Effective Pain Relief — Combines two active ingredients for better pain control.
  • Reduces Fever — Helps bring down high body temperatures.
  • Anti-inflammatory Properties — Reduces swelling and inflammation in the body.

How Long Does It Take to Work?

You may start to feel relief from pain within 30 to 60 minutes after taking Nimfe Plus. The full effect can last for several hours. If you do not notice any improvement after a few days of use, consult your doctor for further advice.

How to Use

Take the tablet with a full glass of water.

Do not chew or crush the tablet.

Follow the dosage prescribed by your doctor.

Take it at regular intervals for best results.

Dosage Guidelines

Adult Dose

The typical adult dose is one tablet every 12 hours, or as directed by your doctor.

Pediatric Dose

Consult your doctor for the appropriate dose for children.

Elderly

Elderly

  • patients may require a lower dose; consult your doctor.

Administration Instructions

Take with or without food, but consistent use with food may help reduce stomach upset.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Overdose Warning

Overdose can lead to serious health issues. Symptoms may include nausea, vomiting, and abdominal pain. If you suspect an overdose, seek immediate medical attention or contact poison control.

Side Effects

Common Side Effects

Nausea

Stomach upset

Dizziness

Less Common Side Effects

Rash

Itching

Serious Side Effects

Liver damage

Severe allergic reactions

When to Seek Immediate Medical Attention

If you experience symptoms like yellowing of the skin or eyes, severe abdominal pain, or difficulty breathing, seek medical help right away.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Nimesulide or Paracetamol — Risk of severe allergic reactions.
  • Severe Liver Disease — Increased risk of liver damage.
  • Active Gastrointestinal Bleeding — Risk of worsening bleeding.

Warnings & Precautions

🤰 Pregnancy
Nimfe Plus is generally not recommended during pregnancy, especially in the third trimester. Always consult your doctor before using any medication during pregnancy.
🤱 Breastfeeding
Paracetamol is considered safe during breastfeeding, but Nimesulide is not recommended. Consult your doctor for advice before using this medication while breastfeeding.
👶 Children
Safety and effectiveness in children have not been established. Consult a pediatrician for appropriate alternatives.
🧓 Elderly
Elderly patients may be more sensitive to the side effects. A lower dose may be necessary; consult your doctor.
🫘 Kidney Disease
Use with caution in patients with kidney impairment. Dose adjustments may be necessary; consult your doctor.
🫁 Liver Disease
Use with caution in patients with liver impairment. Dose adjustments are often required; consult your doctor.
🍷 Alcohol
Avoid alcohol while taking Nimfe Plus, as it can increase the risk of liver damage.
🚗 Driving
This medication may cause dizziness; use caution when driving or operating heavy machinery.

Drug Interactions

Drug-Drug Interactions

Avoid using with other NSAIDs

Consult your doctor if taking anticoagulants

Food Interactions

Taking with food may help reduce stomach upset.

Alcohol Interactions

Alcohol can increase the risk of liver damage.

Disease Interactions

Use with caution in patients with liver or kidney disease.

Storage Instructions

Store at room temperature, away from moisture.

Protect from light.

Keep out of reach of children.

Check expiry date before use.

Expert Advice

Clinical Tips

Always follow your doctor's prescribed dosage.

Do not take for longer than recommended.

Stay hydrated while taking this medication.

Report any unusual side effects to your doctor.

Do not share your medication with others.

Keep track of your symptoms and report any changes.

Use caution when driving or operating machinery.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

Last Updated24 Jun 2026
Content Generated24 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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