Niproz 100mg/325mg Tablet

Generic Name Paracetamol and Nimesulide
Drug Class Analgesic and Anti-inflammatory
Route Oral
Habit Forming No
Prescription Required (Rx)
Strengths 100mg/325mg
MRP
₹37.00
strip of 10 tablets

About Niproz 100mg/325mg Tablet

Niproz 100mg/325mg Tablet is a combination medicine that contains two active ingredients: Paracetamol and Nimesulide. It is primarily used to relieve pain and reduce inflammation. This medicine is commonly prescribed for conditions such as headaches, muscle pain, arthritis, and other types of pain. It is important to follow your doctor's advice on how to use this medication safely and effectively.

Clinical Uses

  • Headache — Relief from mild to moderate headache pain.
  • Muscle Pain — Reduces pain caused by muscle injuries or strains.
  • Arthritis — Helps in managing pain and inflammation in arthritis.
  • Dental Pain — Provides relief from pain after dental procedures.

Uses & Indications

Primary Uses

  • Pain Relief — Effective for managing various types of pain.
  • Anti-inflammatory — Reduces inflammation associated with pain conditions.

Secondary Uses

  • Fever Reduction — Can help lower fever in some cases.

Off-label Uses

  • Menstrual Pain — Sometimes used for relief from menstrual cramps.

How It Works (Mechanism of Action)

Niproz works by combining two active ingredients that help relieve pain and inflammation. Paracetamol reduces pain and fever, while Nimesulide decreases inflammation and swelling.

Paracetamol works primarily in the brain to block pain signals, while Nimesulide inhibits certain enzymes (COX-2) that are involved in the inflammatory process. This dual action makes it effective for various pain-related conditions.

Key Benefits

  • Dual Action — Combines pain relief and anti-inflammatory effects.
  • Fast Relief — Starts working quickly to alleviate pain.
  • Convenient Dosage — Easy to take as a tablet.

How Long Does It Take to Work?

You may start to feel relief from pain within 30 minutes of taking Niproz. The full effect can take a few hours. If your symptoms do not improve after a few days of treatment, consult your doctor.

How to Use

Take the tablet with a full glass of water.

Follow the dosage prescribed by your doctor.

Do not crush or chew the tablet; swallow it whole.

Take it with food if it upsets your stomach.

Dosage Guidelines

Adult Dose

Typically, one tablet every 8-12 hours as needed, not exceeding the recommended daily limit.

Pediatric Dose

Not recommended for children under 12 years without a doctor's advice.

Elderly

Dosage may need adjustment; consult your doctor.

Administration Instructions

Take as directed by your healthcare provider.

Missed Dose

If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once.

Overdose Warning

Overdose can lead to serious health issues. Symptoms may include nausea, vomiting, and abdominal pain. If you suspect an overdose, seek immediate medical attention or call poison control.

Side Effects

Common Side Effects

Nausea

Stomach upset

Dizziness

Less Common Side Effects

Rash

Headache

Serious Side Effects

Severe allergic reactions

Liver damage

When to Seek Immediate Medical Attention

If you experience symptoms like difficulty breathing, swelling of the face or throat, or severe abdominal pain, seek medical help right away.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Nimesulide — Do not use if you have a known allergy to Nimesulide or Paracetamol.
  • Severe Liver Disease — Not safe for patients with severe liver impairment.
  • Active Gastrointestinal Bleeding — Avoid if you have current bleeding issues.

Warnings & Precautions

🤰 Pregnancy
Nimesulide is generally not recommended during pregnancy due to potential risks. Always consult your doctor before using any medication while pregnant.
🤱 Breastfeeding
Paracetamol is considered safe during breastfeeding, but Nimesulide should be avoided. Consult your healthcare provider for advice tailored to your situation.
👶 Children
Use in children under 12 years is not recommended without medical advice. Dosage should be determined by a healthcare professional.
🧓 Elderly
Elderly patients may require dosage adjustments. Consult a doctor for appropriate use in older adults.
🫘 Kidney Disease
Use with caution in patients with kidney impairment. Dose adjustments may be necessary based on kidney function.
🫁 Liver Disease
Nimesulide should be avoided in patients with liver impairment. Paracetamol should be used with caution and under medical supervision.
🍷 Alcohol
Avoid alcohol while taking this medication, as it may increase the risk of liver damage.
🚗 Driving
This medication may cause dizziness; use caution when driving or operating machinery.

Drug Interactions

Drug-Drug Interactions

Avoid using with other NSAIDs

May interact with blood thinners

Food Interactions

Taking with food may help reduce stomach upset.

Alcohol Interactions

Alcohol can increase the risk of liver damage when combined with this medication.

Disease Interactions

Use with caution in patients with liver or kidney disease.

Storage Instructions

Store at room temperature, away from moisture.

Protect from light.

Keep out of reach of children.

Check the expiry date before use.

Expert Advice

Clinical Tips

Always follow your doctor's instructions for dosage.

Do not exceed the recommended dose.

Take with food if you experience stomach upset.

Keep track of your symptoms and report any changes to your doctor.

Do not share your medication with others.

Complete the full course as prescribed.

Store the medication properly to maintain its effectiveness.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

Last Updated24 Jun 2026
Content Generated24 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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