Run 200mg Tablet SR

Run 200mg Tablet SR contains Aceclofenac, which is a non-steroidal anti-inflammatory drug (NSAID). It is used to relieve pain and inflammation in conditions like arthritis, ankylosing spondylitis, and osteoarthritis. This medication is suitable for adults who need relief from pain and swelling. It should be taken as prescribed by a healthcare provider, and it is important to follow the dosage instructions carefully to avoid side effects.

• Osteoarthritis — A condition causing joint pain and stiffness.
• Rheumatoid Arthritis — An autoimmune disorder causing joint inflammation.
• Ankylosing Spondylitis — A type of arthritis affecting the spine.

Primary Uses

Relief of pain and inflammation in osteoarthritis.

Management of rheumatoid arthritis symptoms.

Treatment of ankylosing spondylitis.

Secondary Uses

Relief of mild to moderate pain from other conditions.

Off-label Uses

Not commonly used for off-label purposes.

Aceclofenac works by blocking the action of cyclooxygenase (COX) enzymes. These enzymes are involved in the production of prostaglandins, which are chemicals that promote inflammation, pain, and fever. By inhibiting COX enzymes, Aceclofenac reduces the levels of prostaglandins, thereby decreasing inflammation and pain.

Scientifically, Aceclofenac is a COX-2 selective inhibitor, which means it primarily targets the COX-2 enzyme responsible for inflammation, while having a lesser effect on COX-1, which protects the stomach lining. This selectivity helps in reducing gastrointestinal side effects commonly associated with NSAIDs.

• Pain Relief — Helps reduce pain associated with arthritis and other conditions.
• Anti-inflammatory — Reduces swelling and inflammation in affected joints.
• Improves Mobility — By reducing pain and swelling, it can help improve joint movement.

Initial improvement in pain relief can be noticed within a few hours of taking the tablet. For full therapeutic effects, it may take several days of regular use. If there is no improvement after a week of use, or if symptoms worsen, consult your doctor.

Take the tablet with a full glass of water.

Swallow it whole; do not crush or chew the tablet.

Take it with or after food to minimize stomach upset.

Follow the dosage instructions provided by your doctor.

Do not exceed the recommended dose.

Adult Dose

Typically, one 200mg tablet taken once daily or as directed by a physician.

Pediatric Dose

Not recommended for use in children.

Elderly

Use with caution; dose adjustment may be necessary.

Administration Instructions

Take with food to reduce gastrointestinal discomfort.

Common Side Effects

Nausea

Indigestion

Diarrhea

Less Common Side Effects

Dizziness

Headache

Rash

Serious Side Effects

Severe stomach pain

Blood in stools

Yellowing of the skin or eyes

When to Seek Immediate Medical Attention

Signs of an allergic reaction such as swelling of the face, lips, tongue, or throat.

Severe skin reactions.

• Allergy to NSAIDs — Patients with known hypersensitivity to Aceclofenac or other NSAIDs should not use this medication.
• Active Peptic Ulcer — Use is contraindicated in patients with active or recurrent peptic ulcers.
• Severe Liver or Kidney Disease — Patients with significant hepatic or renal impairment should avoid this medication.

Drug-Drug Interactions

• Warfarin — Increased risk of bleeding.
• Diuretics — Reduced effectiveness of diuretics.
• Other NSAIDs — Increased risk of side effects.

Food Interactions

Take with food to reduce gastrointestinal discomfort.

Alcohol Interactions

Avoid alcohol as it can increase the risk of stomach bleeding.

Disease Interactions

• Peptic Ulcer Disease — Increased risk of gastrointestinal bleeding.
• Kidney Disease — Use with caution.

Store at room temperature (15-25°C).

Keep away from moisture and light.

Keep out of reach of children.

Check the expiry date before use.