Zaspo D 10mg/40mg Tablet

by Aspo Healthcare · Tablet Rx
Generic Name Domperidone and Pantoprazole
Drug Class Antiemetic and Proton Pump Inhibitor
Route Oral
Habit Forming No
Prescription Required (Rx)
Strengths 10mg/40mg
MRP
₹97.00
strip of 10 tablets

About Zaspo D 10mg/40mg Tablet

Zaspo D 10mg/40mg Tablet is a combination medication that contains Domperidone and Pantoprazole. It is primarily used to treat nausea, vomiting, and gastroesophageal reflux disease (GERD). This medicine helps to relieve symptoms by reducing stomach acid and improving the movement of food through the stomach. It is suitable for adults and should be used under the guidance of a healthcare professional.

Clinical Uses

  • Nausea and Vomiting — Helps to control nausea and vomiting caused by various conditions.
  • Gastroesophageal Reflux Disease (GERD) — Reduces acid reflux and associated symptoms.

Uses & Indications

Primary Uses

  • Nausea and Vomiting — Effective in treating nausea and vomiting from different causes.
  • Gastroesophageal Reflux Disease (GERD) — Alleviates symptoms of GERD by reducing stomach acid.

Secondary Uses

  • Functional Dyspepsia — May help in managing symptoms of indigestion.

Off-label Uses

  • Gastroparesis — Sometimes used to improve gastric emptying in patients with delayed gastric emptying.

How It Works (Mechanism of Action)

Zaspo D 10mg/40mg Tablet works by combining two active ingredients. Domperidone helps to increase the movement of the stomach and intestines, which reduces feelings of nausea and prevents vomiting. Pantoprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach, providing relief from acid-related disorders.

The scientific mechanism involves Domperidone blocking dopamine receptors in the gut, enhancing gastric motility. Pantoprazole inhibits the proton pump in the stomach lining, leading to reduced gastric acid secretion. This combination effectively manages symptoms of nausea and acid reflux.

Key Benefits

  • Reduces Nausea — Helps to alleviate feelings of nausea effectively.
  • Controls Vomiting — Prevents vomiting, allowing for better comfort.
  • Decreases Stomach Acid — Reduces the production of stomach acid, helping with acid-related conditions.
  • Improves Digestion — Aids in the movement of food through the digestive tract.

How Long Does It Take to Work?

You may start to feel better within 30 to 60 minutes after taking the tablet. Full treatment duration can vary, but it is typically recommended to continue for as long as prescribed by your doctor. If you do not see any improvement after a week of treatment, consult your healthcare provider.

How to Use

Take the tablet as directed by your doctor.

Swallow the tablet whole with a glass of water.

Do not chew or crush the tablet.

Take it before meals for best results.

Follow the prescribed dosage and schedule.

Dosage Guidelines

Adult Dose

Typically, one tablet once daily before a meal.

Pediatric Dose

Safety and dosage for children should be determined by a healthcare provider.

Elderly

Elderly

  • patients may require dose adjustments; consult your doctor.

Administration Instructions

Take the tablet with water, preferably before meals.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time.

Overdose Warning

In case of overdose, symptoms may include severe dizziness, confusion, or unusual heartbeat. Seek immediate medical attention or contact poison control for guidance.

Side Effects

Common Side Effects

Nausea

Headache

Dizziness

Less Common Side Effects

Dry mouth

Fatigue

Serious Side Effects

Severe allergic reactions

Heart rhythm changes

When to Seek Immediate Medical Attention

If you experience severe side effects such as difficulty breathing, swelling of the face or throat, or chest pain, seek medical help immediately.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Ingredients — Do not use if you are allergic to Domperidone or Pantoprazole.
  • Severe Liver Disease — Not recommended for patients with severe liver impairment.
  • Prolactin-Secreting Tumors — Should not be used in patients with certain tumors that affect prolactin levels.

Warnings & Precautions

🤰 Pregnancy
Zaspo D 10mg/40mg Tablet is classified as Category B in pregnancy. It is generally considered safe, but always consult your doctor before use during pregnancy.
🤱 Breastfeeding
It is not known if this medicine passes into breast milk. Consult your healthcare provider before using it while breastfeeding.
👶 Children
The safety and effectiveness of this medication in children have not been established. Consult a healthcare provider for appropriate alternatives.
🧓 Elderly
Elderly patients may be more sensitive to the effects of this medication. Dose adjustments may be necessary, so consult your doctor.
🫘 Kidney Disease
Use with caution in patients with kidney impairment. Dose adjustments may be required based on the severity of the condition.
🫁 Liver Disease
Use with caution in patients with liver impairment. Dose adjustments may be necessary, especially in severe cases.
💉 Diabetes
Patients with diabetes can generally use this medication, but it is important to monitor blood sugar levels regularly.
🍷 Alcohol
Alcohol may increase the risk of side effects. It is advisable to limit or avoid alcohol while taking this medication.
🚗 Driving
This medication may cause dizziness; avoid driving or operating heavy machinery until you know how it affects you.

Drug Interactions

Drug-Drug Interactions

Avoid taking with other medications that affect heart rhythm.

Consult your doctor if you are using other proton pump inhibitors.

Food Interactions

There are no specific food interactions, but taking it before meals is recommended.

Alcohol Interactions

Alcohol may increase side effects; limit intake.

Disease Interactions

Use with caution in patients with liver or kidney disease.

Storage Instructions

Store at room temperature, away from moisture.

Protect from light.

Keep out of reach of children.

Check expiry date before use.

Expert Advice

Clinical Tips

Always take the medication as prescribed by your doctor.

Do not stop taking it without consulting your healthcare provider.

Keep track of any side effects and report them to your doctor.

Maintain a healthy diet to support treatment.

Stay hydrated while on this medication.

Inform your doctor about all other medications you are taking.

Attend regular follow-up appointments to monitor your condition.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

Last Updated20 Jun 2026
Content Generated20 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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