Zefim-CV Suspension

by Medihealth Lifesciences Pvt. Ltd. · Suspension Schedule H
Generic Name Cefixime, Clavulanic Acid
Drug Class Antibiotic, Beta-lactamase inhibitor
Route Oral
Habit Forming No
Prescription Required (Rx)
Strengths Cefixime 50mg, Clavulanic Acid 31.25mg
MRP
₹79.00
bottle of 30 ml Suspension

About Zefim-CV Suspension

Zefim-CV Suspension is an antibiotic medicine used to treat various bacterial infections. It contains two active ingredients: Cefixime, which is a cephalosporin antibiotic, and Clavulanic Acid, which helps prevent bacteria from becoming resistant to the antibiotic. This medicine is typically prescribed for children and adults to treat infections such as those affecting the respiratory tract, urinary tract, and ear. Patients should use this medicine under the guidance of a healthcare professional and complete the full course to ensure effectiveness.

Clinical Uses

  • Respiratory Tract Infections — Infections affecting the lungs and airways.
  • Urinary Tract Infections — Infections affecting the bladder and urethra.
  • Ear Infections — Infections affecting the middle ear.

Uses & Indications

Primary Uses

Treatment of bacterial infections in the respiratory tract.

Treatment of urinary tract infections.

Treatment of ear infections.

Secondary Uses

May be used for other bacterial infections as determined by a doctor.

Off-label Uses

Not typically used off-label.

How It Works (Mechanism of Action)

Zefim-CV Suspension works by killing bacteria that cause infections. Cefixime interferes with the formation of the bacteria's cell wall, which results in the death of the bacteria. Clavulanic Acid helps prevent bacteria from becoming resistant to Cefixime, making the treatment more effective.

Scientifically, Cefixime binds to penicillin-binding proteins in the bacterial cell wall, inhibiting the final transpeptidation step of peptidoglycan synthesis. This action leads to cell lysis and death. Clavulanic Acid is a beta-lactamase inhibitor that protects Cefixime from degradation by beta-lactamase enzymes produced by resistant bacteria.

Key Benefits

  • Effective against a broad range of bacteria — Helps treat various infections caused by bacteria.
  • Prevents antibiotic resistance — Clavulanic Acid helps prevent bacteria from becoming resistant to Cefixime.
  • Convenient oral suspension — Easy to administer, especially for children.

How Long Does It Take to Work?

Initial improvement in symptoms can be seen within a few days of starting treatment. The full course usually lasts 7 to 14 days, depending on the type and severity of the infection. If there is no improvement after a few days, or if symptoms worsen, consult your doctor.

How to Use

Shake the bottle well before each use to mix the medicine evenly.

Measure the prescribed dose using the measuring cup or spoon provided.

Administer the suspension orally with or without food.

Follow the dosage schedule as prescribed by your doctor.

Complete the full course of treatment even if you feel better.

Dosage Guidelines

Adult Dose

As prescribed by the doctor, typically based on the type and severity of infection.

Pediatric Dose

Based on child's weight and age, as prescribed by the doctor.

Elderly

Dosage adjustments may be necessary based on kidney function.

Administration Instructions

Take the suspension orally, with or without food.

Missed Dose

If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Overdose Warning

In case of an overdose, symptoms may include nausea, vomiting, and diarrhea. Seek immediate medical attention or contact poison control for guidance.

Side Effects

Common Side Effects

Nausea

Diarrhea

Stomach pain

Less Common Side Effects

Headache

Dizziness

Serious Side Effects

Severe allergic reactions

Severe diarrhea

When to Seek Immediate Medical Attention

If you experience difficulty breathing, swelling of the face or throat, or severe rash.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Cefixime or Clavulanic Acid — Patients with known allergies should not use this medicine.
  • Severe Kidney Disease — May require dose adjustment or alternative treatment.

Warnings & Precautions

🤰 Pregnancy
Pregnancy Category B. There are no adequate and well-controlled studies in pregnant women. Use only if clearly needed and prescribed by a doctor.
🤱 Breastfeeding
It is not known if Cefixime or Clavulanic Acid passes into breast milk. Consult your doctor before using this medicine while breastfeeding.
👶 Children
Zefim-CV Suspension is safe for use in children as prescribed by a doctor. Dosage is based on the child's weight and age.
🧓 Elderly
Elderly patients may require dose adjustments based on kidney function. Consult a doctor for appropriate dosing.
🫘 Kidney Disease
Patients with kidney impairment may need dose adjustments. Consult your doctor for advice.
🫁 Liver Disease
Use with caution in patients with liver impairment. Dose adjustment may be necessary.
💉 Diabetes
Zefim-CV Suspension does not directly affect blood sugar levels, but consult your doctor for personalized advice.
🍷 Alcohol
Avoid alcohol while taking this medicine as it may increase the risk of side effects.
🚗 Driving
Zefim-CV Suspension does not typically affect your ability to drive, but if you experience dizziness, avoid driving.

Drug Interactions

Drug-Drug Interactions

Warfarin

Probenecid

Food Interactions

No significant food interactions.

Alcohol Interactions

Avoid alcohol to prevent increased side effects.

Disease Interactions

Kidney disease

Liver disease

Storage Instructions

Store at room temperature (below 25°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check the expiry date before use.

Expert Advice

Clinical Tips

Complete the full course of treatment even if you feel better.

Shake the bottle well before each use.

Measure the dose accurately using the provided measuring device.

Do not share your medicine with others.

Inform your doctor of any other medications you are taking.

Avoid alcohol during treatment.

Consult your doctor if you experience severe side effects.

Store the medicine as per the instructions to maintain its effectiveness.

Report any signs of an allergic reaction immediately.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Frequently Asked Questions

Can I take Zefim-CV Suspension if I have a penicillin allergy?
You should consult your healthcare provider, as there may be a risk of cross-reactivity.
How long will I need to take this medication?
The duration of treatment will depend on the type and severity of the infection; follow your doctor's instructions.
What should I do if I miss a dose?
Take the missed dose as soon as you remember, but skip it if it's almost time for the next dose; do not double up.

Sources

The information on this page about Zefim-CV Suspension has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.

  1. Manufacturer – Zefim-CV Suspension Prescribing Information and Product Monograph
  2. NHSCefixime: antibiotic used to treat bacterial infections
  3. MedlinePlusCefixime Oral: Uses, Side Effects, Interactions
  4. Drugs.comCefixime and Clavulanic Acid
  5. DrugBankCefixime
Last Updated12 Jun 2026
Content Generated12 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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