Zefxone 500mg Injection

by Gurgrace Pharmaceuticals · Injection Schedule H
Generic Name Ceftriaxone
Drug Class Cephalosporin antibiotic
Route Intravenous / Intramuscular
Habit Forming No
Prescription Required (Rx)
Strengths 500mg, 1g, 2g
MRP
₹48.00
vial of 1 Injection

About Zefxone 500mg Injection

Zefxone 500mg Injection contains the active ingredient Ceftriaxone, which is a cephalosporin antibiotic. It is used to treat a wide range of bacterial infections, including those affecting the lungs, urinary tract, skin, and brain. This medication is typically administered in a hospital or clinical setting by a healthcare professional. It is important for patients to complete the full course of treatment as prescribed, even if they start to feel better, to ensure the infection is fully cleared.

Clinical Uses

  • Bacterial Infections — Treats infections caused by bacteria in various parts of the body.
  • Pneumonia — Used to treat lung infections.
  • Urinary Tract Infections — Effective against infections of the urinary system.
  • Skin Infections — Treats bacterial infections of the skin.
  • Meningitis — Used for bacterial infections of the brain and spinal cord.

Uses & Indications

Primary Uses

  • Bacterial Infections — Treats a variety of infections caused by bacteria.
  • Pneumonia — Effective in treating lung infections.

Secondary Uses

  • Urinary Tract Infections — Used for infections of the urinary system.
  • Skin Infections — Treats bacterial skin infections.

Off-label Uses

  • Prophylaxis in Surgery — Sometimes used to prevent infections before surgery.

How It Works (Mechanism of Action)

Ceftriaxone works by killing bacteria or preventing their growth. It does this by interfering with the formation of the bacteria's cell wall, which is essential for their survival.

Scientifically, Ceftriaxone binds to specific penicillin-binding proteins inside the bacterial cell wall. This inhibits the final stages of bacterial cell wall synthesis, leading to cell lysis and death.

Key Benefits

  • Broad-Spectrum Activity — Effective against a wide range of bacteria.
  • Convenient Dosing — Can be administered once daily.
  • Effective for Severe Infections — Suitable for serious infections like meningitis.

How Long Does It Take to Work?

Initial improvement in symptoms is usually seen within a few days of starting treatment. The full course of treatment typically lasts from 7 to 14 days, depending on the type and severity of the infection. If there is no improvement after 3-4 days, or if symptoms worsen, consult your doctor.

How to Use

Ensure the injection is administered by a healthcare professional.

Follow the prescribed dosage and schedule as advised by your doctor.

Do not self-administer this medication.

Complete the full course of treatment, even if you feel better.

Dosage Guidelines

Adult Dose

Typically 1-2g once daily, depending on the infection type and severity.

Pediatric Dose

Dosage is based on body weight and type of infection.

Elderly

Same as adult dose, but with close monitoring.

Administration Instructions

Administered via intravenous or intramuscular injection by a healthcare professional.

Missed Dose

If you miss a dose, contact your healthcare provider for advice. Do not double the dose to make up for a missed one.

Overdose Warning

In case of an overdose, seek immediate medical attention. Symptoms may include nausea, vomiting, and diarrhea. Contact emergency services or poison control for guidance.

Side Effects

Common Side Effects

Diarrhea

Nausea

Rash

Less Common Side Effects

Headache

Dizziness

Serious Side Effects

Severe allergic reactions

Severe diarrhea

When to Seek Immediate Medical Attention

Signs of an allergic reaction, such as difficulty breathing, swelling of the face, lips, tongue, or throat.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Cephalosporins — Patients with known allergy should not use this medication.
  • Severe Liver Disease — Use with caution in patients with severe liver impairment.

Warnings & Precautions

🤰 Pregnancy
Category B. Ceftriaxone should be used during pregnancy only if clearly needed and prescribed by a doctor.
🤱 Breastfeeding
Ceftriaxone is excreted in breast milk in small amounts. Consult your doctor before using this medication while breastfeeding.
👶 Children
Ceftriaxone can be used in children, with dosage adjusted based on body weight and infection type. Consult a pediatrician for appropriate dosing.
🧓 Elderly
Elderly patients can use Ceftriaxone, but they should be monitored closely for any adverse effects due to potential age-related organ function decline.
🫘 Kidney Disease
In patients with severe renal impairment, dosage adjustment may be necessary. Consult your doctor for specific recommendations.
🫁 Liver Disease
Use with caution in patients with severe liver impairment. Dosage adjustments may be required based on liver function tests.
💉 Diabetes
Ceftriaxone does not typically affect blood sugar levels, but diabetic patients should monitor their blood sugar as a precaution.
🍷 Alcohol
There are no known interactions between Ceftriaxone and alcohol, but it is advisable to limit alcohol consumption during treatment.
🚗 Driving
Ceftriaxone does not usually affect your ability to drive or operate machinery.

Drug Interactions

Drug-Drug Interactions

Calcium-containing IV solutions

Warfarin

Food Interactions

No significant food interactions.

Alcohol Interactions

No significant interactions with alcohol.

Disease Interactions

Colitis

Renal impairment

Storage Instructions

Store at room temperature below 25°C.

Keep away from moisture and light.

Keep out of reach of children.

Check the expiry date before use.

Expert Advice

Clinical Tips

Complete the full course of treatment as prescribed.

Inform your doctor of any allergies before starting treatment.

Do not self-administer; ensure it is given by a healthcare professional.

Report any severe side effects to your doctor immediately.

Do not mix with calcium-containing IV solutions.

Keep hydrated and maintain a balanced diet during treatment.

Inform your doctor of any other medications you are taking.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Frequently Asked Questions

What should I do if I miss a dose?
If you miss a dose, contact your healthcare provider for instructions. Do not double the dose to catch up.
Can I take Zefxone for viral infections?
No, Zefxone is an antibiotic and is not effective against viral infections like the common cold or flu.
How long will I need to take Zefxone?
The duration of treatment depends on the type of infection and your response to the medication, as determined by your healthcare provider.

Sources

The information on this page about Zefxone 500mg Injection has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.

  1. Manufacturer – Zefxone 500mg Injection Prescribing Information and Product Monograph
  2. NHSCeftriaxone: antibiotic used to treat serious infections
  3. Mayo ClinicCeftriaxone (Injection Route)
  4. MedlinePlusCeftriaxone Injection
  5. DrugBankCeftriaxone
Last Updated12 Jun 2026
Content Generated12 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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