Zelcef TZ 1000mg/125mg Injection

Zelcef TZ 1000mg/125mg Injection is a combination antibiotic used to treat various bacterial infections. It contains Ceftriaxone, which fights bacteria, and Tazobactam, which helps Ceftriaxone work better. This medicine is usually given in a hospital or clinic by a healthcare professional. It is important for patients with infections that are caused by certain bacteria to use this medicine as prescribed by their doctor.

• Pneumonia — A lung infection that causes cough and difficulty breathing.
• Urinary Tract Infections — Infections in the urinary system, causing pain and frequent urination.
• Skin Infections — Infections affecting the skin and soft tissues.
• Intra-abdominal Infections — Infections within the abdominal cavity.
• Sepsis — A severe infection that spreads throughout the body.

Primary Uses

• Pneumonia — Treats bacterial infections in the lungs.
• Urinary Tract Infections — Effective against infections in the urinary system.

Secondary Uses

• Skin Infections — Helps in treating various skin infections.
• Intra-abdominal Infections — Used for infections in the abdominal area.

Off-label Uses

• Sepsis — May be used in severe cases of infection.

Ceftriaxone works by stopping the growth of bacteria. It does this by interfering with the bacteria's ability to form cell walls, which are essential for their survival. When the cell wall is weakened, the bacteria cannot grow and multiply, leading to their death.

Tazobactam is a beta-lactamase inhibitor. It protects Ceftriaxone from being broken down by certain enzymes produced by bacteria. This combination allows Ceftriaxone to remain effective against bacteria that would otherwise resist treatment.

• Broad-Spectrum Activity — Effective against a wide range of bacteria.
• Enhanced Efficacy — Tazobactam helps Ceftriaxone work better against resistant bacteria.
• Quick Action — Starts working quickly to reduce infection symptoms.

You may start to feel better within a few days of treatment. However, it is important to complete the full course of treatment as prescribed by your doctor, which usually lasts several days. If you do not see any improvement after a few days, contact your doctor for further advice.

Ensure the injection is prepared by a healthcare professional.

Receive the injection in a hospital or clinic setting.

Follow the healthcare provider's instructions regarding dosage and frequency.

Do not self-administer this injection.

Adult Dose

The typical adult dose is 1000mg of Ceftriaxone and 125mg of Tazobactam, administered once daily or as directed by a healthcare provider.

Pediatric Dose

For children

• , the dose is based on body weight and must be determined by a healthcare provider.

Elderly

Elderly

• patients may require dose adjustments based on kidney function.

Administration Instructions

This injection should be given by a healthcare professional, usually in a hospital or clinic.

Common Side Effects

Nausea

Diarrhea

Injection site reactions

Less Common Side Effects

Headache

Rash

Serious Side Effects

Severe allergic reactions

Clostridium difficile infection

When to Seek Immediate Medical Attention

If you experience difficulty breathing, swelling of the face or throat, or severe diarrhea, seek medical help right away.

• Allergy to Ceftriaxone — Patients with a known allergy should not use this medicine.
• Allergy to Tazobactam — Avoid use if allergic to Tazobactam.
• Severe Liver Disease — Patients with severe liver impairment should not use this medicine.

Drug-Drug Interactions

Avoid using with other antibiotics unless directed by a doctor.

May interact with anticoagulants, increasing bleeding risk.

Food Interactions

There are no specific food interactions, but it is best to take it as directed by your healthcare provider.

Alcohol Interactions

Alcohol may increase the risk of side effects; avoid drinking while on this medication.

Disease Interactions

Use caution in patients with a history of gastrointestinal disease or kidney problems.

Store at room temperature.

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check expiry date before use.