Zelpar Plus Syrup

by Zelnic Biotech Pvt Ltd · Syrup OTC
Generic Name Paracetamol and Mefenamic Acid
Drug Class Analgesic and Anti-inflammatory
Route Oral
Habit Forming No
Prescription Not Required
Strengths 125mg/50mg
MRP
₹42.00
bottle of 60 ml Syrup

About Zelpar Plus Syrup

Zelpar Plus Syrup is a combination medicine that contains Paracetamol and Mefenamic Acid. It is used to relieve pain and reduce fever. This syrup is suitable for adults and children who need quick relief from mild to moderate pain, such as headaches, toothaches, or menstrual cramps. Always follow the dosage instructions provided by your healthcare provider or on the label.

Clinical Uses

  • Fever — Helps to lower body temperature during fever.
  • Headache — Provides relief from mild to moderate headaches.
  • Menstrual Pain — Alleviates pain associated with menstruation.
  • Toothache — Eases discomfort from dental pain.

Uses & Indications

Primary Uses

  • Pain Relief — Used to relieve various types of pain including headaches and muscle aches.
  • Fever Reduction — Effective in lowering fever in adults and children.

Secondary Uses

  • Menstrual Cramps — Helps in reducing pain during menstrual periods.
  • Post-operative Pain — Can be used for pain relief after surgical procedures.

Off-label Uses

  • Arthritis Pain — Sometimes used to manage pain in arthritis patients.

How It Works (Mechanism of Action)

Zelpar Plus Syrup works by combining two active ingredients: Paracetamol and Mefenamic Acid. Paracetamol reduces pain and fever by acting on the brain, while Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) that decreases inflammation and pain in the body.

Paracetamol inhibits the production of prostaglandins, which are chemicals in the body that cause pain and fever. Mefenamic Acid works by blocking the enzymes that produce these prostaglandins, thus providing relief from pain and inflammation. Together, they provide a synergistic effect for better pain management.

Key Benefits

  • Effective Pain Relief — Combines two medications for better pain management.
  • Quick Action — Starts working within 30 minutes to relieve pain.
  • Reduces Fever — Helps to bring down fever effectively.

How Long Does It Take to Work?

You may start to feel relief within 30 minutes after taking Zelpar Plus Syrup. For full effect, it may take a few hours. If your symptoms do not improve after 3 days, or if they worsen, consult your doctor.

How to Use

Shake the bottle well before use.

Measure the correct dose using the provided measuring cup.

Take the syrup with or without food as directed.

Do not exceed the recommended dose.

Store the syrup in a cool, dry place.

Dosage Guidelines

Adult Dose

The typical dose for adults is 10-15 ml every 6-8 hours as needed, not exceeding 60 ml in 24 hours.

Pediatric Dose

For children

  • , the dose is based on weight. Consult a doctor for the appropriate dosage.

Elderly

Elderly

  • patients should use the lowest effective dose to minimize side effects.

Administration Instructions

Take the syrup as directed by your healthcare provider. Do not take more than the recommended dose.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time.

Overdose Warning

Taking too much Zelpar Plus Syrup can lead to serious health issues. Symptoms of overdose may include nausea, vomiting, loss of appetite, confusion, and jaundice. If you suspect an overdose, seek medical help immediately or contact poison control.

Side Effects

Common Side Effects

Nausea

Vomiting

Stomach pain

Less Common Side Effects

Rash

Dizziness

Serious Side Effects

Severe allergic reactions

Signs of liver damage (e.g., yellowing of skin or eyes)

When to Seek Immediate Medical Attention

If you experience severe side effects or signs of an allergic reaction, seek medical help right away.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Ingredients — Do not use if you are allergic to Paracetamol or Mefenamic Acid.
  • Severe Liver Disease — Not recommended for patients with severe liver problems.
  • Active Peptic Ulcer — Avoid use if you have an active stomach ulcer.

Warnings & Precautions

🤰 Pregnancy
Zelpar Plus Syrup is generally not recommended during pregnancy unless advised by a doctor. Always consult your healthcare provider before using any medication during pregnancy.
🤱 Breastfeeding
Paracetamol is considered safe during breastfeeding, but Mefenamic Acid may pass into breast milk. Consult your doctor before using this syrup while breastfeeding.
👶 Children
Zelpar Plus Syrup can be used in children, but the dosage must be determined by a healthcare provider based on the child's weight and age.
🧓 Elderly
Elderly patients should use this medication with caution and may require a lower dose to avoid side effects.
🫘 Kidney Disease
Patients with kidney impairment should use Zelpar Plus Syrup with caution. Dose adjustments may be necessary based on the severity of kidney function.
🫁 Liver Disease
This medicine should be used with caution in patients with liver impairment. Dose adjustments may be needed, and it is important to monitor liver function.
🍷 Alcohol
Avoid consuming alcohol while taking Zelpar Plus Syrup, as it may increase the risk of liver damage.
🚗 Driving
Zelpar Plus Syrup does not typically affect your ability to drive or operate machinery.

Drug Interactions

Drug-Drug Interactions

Avoid taking with other NSAIDs

Consult your doctor if you are taking blood thinners

Food Interactions

There are no specific food interactions, but taking it with food may help reduce stomach upset.

Alcohol Interactions

Do not drink alcohol while taking this medicine to avoid liver damage.

Disease Interactions

Use with caution in patients with liver or kidney disease.

Storage Instructions

Store at room temperature (15-30°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check the expiry date before use.

Expert Advice

Clinical Tips

Always follow the recommended dosage.

Do not use for longer than advised.

Shake the bottle well before each use.

Store in a cool, dry place.

Consult your doctor if symptoms persist.

Do not share this medicine with others.

Report any unusual side effects to your doctor.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

Last Updated22 Jun 2026
Content Generated22 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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