Zeopenem 125mg Injection

by Sigma Softgel Formulation · Injection Schedule H1
Generic Name Meropenem
Drug Class Carbapenem antibiotic
Route Intravenous
Habit Forming No
Prescription Required (Rx)
Strengths 125mg, 250mg, 500mg, 1g
MRP
₹280.00
vial of 1 Injection

About Zeopenem 125mg Injection

Zeopenem 125mg Injection contains the active ingredient Meropenem, which is a broad-spectrum antibiotic used to treat severe bacterial infections. It is effective against a wide range of bacteria and is commonly used in hospitals for treating infections of the lungs, abdomen, and urinary tract, among others. This medication is administered intravenously, meaning it is given directly into a vein by a healthcare professional. It is important for patients to complete the full course of treatment as prescribed by their doctor to ensure the infection is fully cleared.

Clinical Uses

  • Severe Pneumonia — A serious lung infection that requires hospitalization.
  • Intra-abdominal Infections — Infections within the abdominal cavity.
  • Urinary Tract Infections — Serious infections of the urinary system.
  • Skin and Soft Tissue Infections — Severe infections affecting the skin and underlying tissues.

Uses & Indications

Primary Uses

Treatment of severe bacterial infections.

Used in hospital settings for critical infections.

Secondary Uses

Prophylaxis in surgical procedures to prevent infection.

Off-label Uses

Used in certain cases of meningitis under medical supervision.

How It Works (Mechanism of Action)

Meropenem works by killing bacteria that cause infections. It does this by interfering with the bacteria's ability to form cell walls, which are essential for their survival.

Scientifically, Meropenem is a beta-lactam antibiotic that binds to penicillin-binding proteins, inhibiting the synthesis of peptidoglycan, an essential component of the bacterial cell wall. This leads to cell lysis and death of the bacteria.

Key Benefits

  • Broad-Spectrum Activity — Effective against a wide range of bacteria.
  • Rapid Action — Quickly reduces bacterial load in severe infections.
  • Hospital Use — Suitable for critical care settings.

How Long Does It Take to Work?

Initial improvement in symptoms can be seen within a few days of starting treatment. The full course of treatment typically lasts 7 to 14 days, depending on the infection. If there is no improvement within 3 to 5 days, consult your doctor.

How to Use

Ensure the injection is prepared by a healthcare professional.

Administer the injection intravenously as directed by your doctor.

Complete the full course of treatment, even if you feel better.

Do not self-administer unless trained to do so.

Follow any additional instructions provided by your healthcare provider.

Dosage Guidelines

Adult Dose

Typically 500mg to 1g every 8 hours, depending on the infection.

Pediatric Dose

Dosage is based on body weight and type of infection.

Elderly

Dosage adjustments may be necessary based on kidney function.

Administration Instructions

Administered intravenously by a healthcare professional.

Missed Dose

If you miss a dose, contact your healthcare provider for advice. Do not double the dose to make up for a missed one.

Overdose Warning

In case of an overdose, symptoms may include seizures, confusion, or severe allergic reactions. Seek immediate medical attention or contact emergency services.

Side Effects

Common Side Effects

Nausea

Diarrhea

Headache

Less Common Side Effects

Rash

Vomiting

Serious Side Effects

Severe allergic reactions

Seizures

When to Seek Immediate Medical Attention

Difficulty breathing

Swelling of the face or throat

Severe skin reactions

Contraindications — Who Should Not Use This Medicine

  • Allergy to Meropenem — Patients with known hypersensitivity should not use this medication.
  • Severe Renal Impairment — Use with caution and under medical supervision.

Warnings & Precautions

🤰 Pregnancy
Category B. Animal studies have not shown harm to the fetus, but there are no adequate studies in pregnant women. Use only if clearly needed and prescribed by a doctor.
🤱 Breastfeeding
Meropenem is excreted in breast milk in small amounts. Consult your doctor before using this medication while breastfeeding.
👶 Children
Safe for use in children under medical supervision. Dosage is based on body weight and type of infection.
🧓 Elderly
Generally safe for elderly patients, but dosage adjustments may be necessary based on kidney function.
🫘 Kidney Disease
Patients with renal impairment may require dosage adjustments. Consult your doctor for appropriate dosing.
🫁 Liver Disease
Use with caution in patients with liver impairment. No specific dosage adjustments are typically required.
💉 Diabetes
Meropenem does not typically affect blood sugar levels. Diabetic patients should monitor their blood sugar as usual.
🍷 Alcohol
There are no known interactions between Meropenem and alcohol, but it is best to avoid alcohol to ensure optimal recovery.
🚗 Driving
Meropenem does not usually affect your ability to drive or operate machinery.

Drug Interactions

Drug-Drug Interactions

  • Probenecid — May increase levels of Meropenem in the blood.
  • Valproic Acid — May reduce the effectiveness of valproic acid.

Food Interactions

No significant food interactions.

Alcohol Interactions

No known interactions with alcohol.

Disease Interactions

  • Renal impairment — Dosage adjustments may be necessary.

Storage Instructions

Store at room temperature between 20-25°C (68-77°F).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check the expiry date before use.

Expert Advice

Clinical Tips

Complete the full course of treatment as prescribed.

Inform your doctor of any allergies before starting treatment.

Report any severe side effects to your healthcare provider immediately.

Do not self-administer unless trained to do so.

Inform your doctor of any other medications you are taking.

Do not stop the medication abruptly without consulting your doctor.

Maintain hydration during treatment.

Inform your doctor if you are pregnant or breastfeeding.

Regularly monitor kidney function if you have renal impairment.

Consult your doctor if symptoms do not improve within a few days.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Frequently Asked Questions

What should I do if I miss a dose?
If you miss a dose, contact your healthcare provider for instructions on what to do.
Can I take Zeopenem with other medications?
Always inform your healthcare provider about all medications you are taking to avoid potential interactions.
How long will I need to take Zeopenem?
The duration of treatment will depend on the type and severity of the infection, as determined by your healthcare provider.

Sources

The information on this page about Zeopenem 125mg Injection has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.

  1. Manufacturer – Zeopenem 125mg Injection Prescribing Information and Product Monograph
  2. NHSMeropenem
  3. Mayo ClinicMeropenem (Intravenous Route)
  4. MedlinePlusMeropenem Injection
  5. DailyMedMeropenem - Meropenem Injection
Last Updated13 Jun 2026
Content Generated13 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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