Zerox-SM 1000mg/500mg Injection

by Pharmacon Healthcare · Injection Schedule H
Generic Name Ceftriaxone and Sulbactam
Drug Class Antibiotic
Route Intravenous
Habit Forming No
Prescription Required (Rx)
Strengths 1000mg/500mg
MRP
₹140.00
vial of 1 Powder for Injection

About Zerox-SM 1000mg/500mg Injection

Zerox-SM Injection is a combination of two antibiotics, Ceftriaxone and Sulbactam. It is used to treat various bacterial infections in the body. This medicine is usually given in a hospital or clinic by a healthcare professional. It helps fight infections effectively and is important for patients who need strong antibiotic treatment.

Clinical Uses

  • Severe Infections — Used for serious bacterial infections in the body.
  • Pneumonia — Treats lung infections caused by bacteria.
  • Urinary Tract Infections — Effective against infections in the urinary system.
  • Skin Infections — Helps in treating bacterial skin infections.
  • Intra-abdominal Infections — Used for infections within the abdominal cavity.

Uses & Indications

Primary Uses

  • Severe Bacterial Infections — Treats life-threatening infections caused by bacteria.
  • Pneumonia — Effective for treating lung infections.

Secondary Uses

  • Urinary Tract Infections — Used for infections in the urinary system.
  • Skin and Soft Tissue Infections — Treats infections affecting the skin.

How It Works (Mechanism of Action)

Ceftriaxone works by stopping the growth of bacteria. It does this by interfering with the bacteria's ability to form cell walls, which are essential for their survival. Without a proper cell wall, bacteria cannot maintain their structure and eventually die off.

Sulbactam is a beta-lactamase inhibitor. It protects Ceftriaxone from being broken down by certain enzymes that bacteria produce to resist antibiotics. This combination makes the treatment more effective against resistant strains of bacteria.

Key Benefits

  • Broad-Spectrum Activity — Works against a wide range of bacteria.
  • Combination Therapy — Sulbactam helps protect Ceftriaxone from being broken down by bacteria.
  • Effective Against Resistant Bacteria — Useful for infections caused by bacteria that are hard to treat.

How Long Does It Take to Work?

You may start to feel better within a few days of starting treatment. The full course usually lasts from 5 to 14 days, depending on the infection. If you do not see improvement after a few days, contact your doctor.

How to Use

Ensure the injection is prepared by a healthcare professional.

Receive the injection in a hospital or clinic setting.

Follow the prescribed schedule for the injections.

Do not self-administer the injection.

Dosage Guidelines

Adult Dose

The typical adult dose is 1000mg of Ceftriaxone and 500mg of Sulbactam, given once a day or as directed by a doctor.

Pediatric Dose

For children

  • , the dosage is based on their weight and the type of infection. Consult a doctor for the correct dose.

Elderly

Elderly

  • patients may require dose adjustments based on kidney function.

Administration Instructions

Administered by a healthcare professional via intravenous injection.

Missed Dose

If you miss a dose, contact your healthcare provider immediately. Do not double the dose to make up for the missed one.

Overdose Warning

Overdose can lead to serious side effects. Symptoms may include severe allergic reactions or gastrointestinal issues. If you suspect an overdose, seek immediate medical help or call emergency services.

Side Effects

Common Side Effects

Nausea

Diarrhea

Rash

Less Common Side Effects

Headache

Dizziness

Serious Side Effects

Severe allergic reactions

Liver problems

When to Seek Immediate Medical Attention

If you experience difficulty breathing, swelling of the face or throat, or severe abdominal pain, seek medical help right away.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Ceftriaxone — Patients with a known allergy should not use this medicine.
  • Severe Liver Disease — Not recommended for patients with significant liver impairment.

Warnings & Precautions

🤰 Pregnancy
Ceftriaxone is generally considered safe during pregnancy, but always consult your doctor before use. It is important to weigh the benefits against any potential risks.
🤱 Breastfeeding
Ceftriaxone passes into breast milk in small amounts. Consult your doctor before using this medicine while breastfeeding to ensure safety for your baby.
👶 Children
The safety and effectiveness of this medicine in children depend on the specific condition being treated. Always consult a pediatrician for appropriate dosing.
🧓 Elderly
Elderly patients may be more sensitive to side effects. Dosage adjustments may be necessary based on kidney function.
🫘 Kidney Disease
In patients with kidney impairment, the dose may need to be adjusted. Regular monitoring of kidney function is recommended.
🫁 Liver Disease
Use with caution in patients with liver impairment. Dose adjustments may be necessary based on liver function tests.
🍷 Alcohol
Alcohol may interfere with the effectiveness of the treatment. It is advisable to avoid alcohol while using this medicine.
🚗 Driving
This medicine may cause dizziness in some patients, so be cautious when driving or operating machinery.

Drug Interactions

Drug-Drug Interactions

Avoid using with other antibiotics unless prescribed.

Anticoagulants may increase bleeding risk.

Food Interactions

There are no specific food interactions, but it's best to take it on an empty stomach.

Alcohol Interactions

Alcohol can reduce the effectiveness of the treatment.

Disease Interactions

Use caution in patients with liver or kidney disease.

Storage Instructions

Store at room temperature.

Keep away from moisture.

Protect from light.

Keep away from children.

Check expiry date before use.

Expert Advice

Clinical Tips

Complete the full course of treatment as prescribed.

Do not share this medicine with others.

Inform your doctor about any allergies.

Stay hydrated during treatment.

Report any unusual side effects to your doctor.

Do not stop the treatment early, even if you feel better.

Follow up with your doctor if symptoms do not improve.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

Last Updated22 Jun 2026
Content Generated22 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
Scroll to Top