Zerox-TZ 1000mg/125mg Injection

by Pharmacon Healthcare · Injection Schedule H
Generic Name Ceftriaxone and Tazobactam
Drug Class Antibiotic
Route Intravenous
Habit Forming No
Prescription Required (Rx)
Strengths 1000mg/125mg
MRP
₹210.00
vial of 1 Powder for Injection

About Zerox-TZ 1000mg/125mg Injection

Zerox-TZ 1000mg/125mg Injection is a combination of two antibiotics, Ceftriaxone and Tazobactam. It is used to treat serious infections caused by bacteria. This medicine is usually given in a hospital or clinic by a healthcare professional. It is important for patients with bacterial infections to receive this treatment to help their body fight off the infection effectively.

Clinical Uses

  • Severe Infections — Used for treating severe bacterial infections.
  • Pneumonia — Effective against pneumonia caused by bacteria.
  • Urinary Tract Infections — Treats complicated urinary tract infections.
  • Skin Infections — Used for serious skin infections caused by bacteria.

Uses & Indications

Primary Uses

  • Severe Infections — Treats serious infections caused by bacteria.
  • Pneumonia — Effective for bacterial pneumonia.

Secondary Uses

  • Urinary Tract Infections — Used for complicated urinary tract infections.
  • Skin Infections — Treats serious skin infections.

How It Works (Mechanism of Action)

Ceftriaxone works by stopping the growth of bacteria. It does this by interfering with the bacteria's ability to form cell walls, which are essential for their survival. Without a proper cell wall, bacteria cannot thrive and multiply, leading to their death.

Tazobactam is a beta-lactamase inhibitor. It protects Ceftriaxone from being broken down by certain enzymes that bacteria produce to resist antibiotics. This combination allows Ceftriaxone to remain effective against bacteria that would otherwise be resistant.

Key Benefits

  • Broad-Spectrum Activity — Works against a wide range of bacteria.
  • Combination Therapy — Tazobactam helps enhance the effect of Ceftriaxone.
  • Effective Against Resistant Bacteria — Useful in treating infections caused by resistant strains.

How Long Does It Take to Work?

You may start to feel better within a few days of starting treatment. However, it is important to complete the full course of the injection as prescribed by your doctor, which usually lasts from a few days to a week. If you do not see improvement after a few days, contact your doctor.

How to Use

Ensure the injection is prepared by a healthcare professional.

Receive the injection into a vein or muscle as directed.

Do not self-administer the injection.

Follow the schedule provided by your healthcare provider.

Dosage Guidelines

Adult Dose

The typical adult dose is 1000mg of Ceftriaxone and 125mg of Tazobactam, given once daily or as directed by a doctor.

Pediatric Dose

Dosage for children is based on weight and should be determined by a healthcare provider.

Elderly

Elderly

  • patients may require dose adjustments based on kidney function.

Administration Instructions

Administered by a healthcare professional in a clinical setting.

Missed Dose

If you miss a dose, contact your healthcare provider for instructions. Do not double the dose to make up for the missed one.

Overdose Warning

Overdose symptoms may include severe allergic reactions, confusion, or seizures. If you suspect an overdose, seek immediate medical attention or call emergency services.

Side Effects

Common Side Effects

Nausea

Diarrhea

Rash

Less Common Side Effects

Headache

Dizziness

Serious Side Effects

Severe allergic reactions

Liver problems

When to Seek Immediate Medical Attention

If you experience difficulty breathing, swelling of the face or throat, or severe abdominal pain, seek medical help right away.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Ceftriaxone — Patients with a known allergy should not use this medicine.
  • Allergy to Tazobactam — Avoid use in patients allergic to Tazobactam.

Warnings & Precautions

🤰 Pregnancy
Ceftriaxone and Tazobactam are generally considered safe during pregnancy. However, always consult your doctor before use to weigh the benefits and risks.
🤱 Breastfeeding
Ceftriaxone and Tazobactam can pass into breast milk. Consult your doctor before using this medication while breastfeeding.
👶 Children
The safety and effectiveness of this medicine in children should be determined by a healthcare provider. Dosage is usually based on the child's weight.
🧓 Elderly
Elderly patients may be more sensitive to side effects. Dosage adjustments may be necessary based on kidney function.
🫘 Kidney Disease
Ceftriaxone is primarily eliminated through the kidneys. Patients with renal impairment may require dose adjustments.
🫁 Liver Disease
Use with caution in patients with liver impairment. Dose adjustments may be necessary based on liver function.
🍷 Alcohol
Alcohol should be avoided while receiving this treatment as it may increase the risk of side effects.
🚗 Driving
This medicine may cause dizziness; use caution when driving or operating machinery.

Drug Interactions

Drug-Drug Interactions

Avoid using with other antibiotics without consulting a doctor.

May interact with anticoagulants, increasing bleeding risk.

Food Interactions

No significant food interactions are known.

Alcohol Interactions

Alcohol may increase side effects; avoid consumption.

Disease Interactions

Use with caution in patients with a history of liver or kidney disease.

Storage Instructions

Store at room temperature.

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check expiry date before use.

Expert Advice

Clinical Tips

Complete the full course of treatment as prescribed.

Do not share this medicine with others.

Report any unusual side effects to your doctor.

Stay hydrated while on treatment.

Inform your doctor about all other medications you are taking.

Do not stop the treatment early, even if you feel better.

Attend follow-up appointments as advised.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

Last Updated22 Jun 2026
Content Generated22 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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