Zerther 150mg Injection

Zerther 150mg Injection contains Alpha-Beta Arteether, an antimalarial medication used to treat severe malaria caused by Plasmodium falciparum. It is administered intramuscularly and is typically used when oral medications are not suitable. This injection is meant for use under medical supervision, especially in hospital settings. It is important for patients with malaria to complete the full course of treatment as prescribed by their healthcare provider to ensure the infection is fully cleared.

• Severe Malaria — Used to treat severe malaria infections caused by Plasmodium falciparum.

Primary Uses

Treatment of severe malaria caused by Plasmodium falciparum.

Secondary Uses

Off-label Uses

Zerther 150mg Injection works by interfering with the growth of the malaria parasite in the red blood cells. This helps in reducing the number of parasites in the blood, thereby alleviating the symptoms of malaria.

Scientifically, Alpha-Beta Arteether acts by inhibiting the nucleic acid and protein synthesis of the parasite, leading to its death. It disrupts the parasite's mitochondrial function, which is essential for its survival.

• Rapid Action — Provides quick relief from severe malaria symptoms.
• Effective Treatment — Targets the malaria parasite effectively to reduce infection.

Initial improvement in symptoms can be observed within 24-48 hours of administration. The full course of treatment typically lasts for 3-5 days. If there is no improvement in symptoms within 48 hours, it is important to consult a doctor.

The injection should be administered by a healthcare professional.

It is given intramuscularly, usually in a hospital setting.

Follow the dosage and schedule as prescribed by your doctor.

Complete the full course of treatment even if you start feeling better.

Adult Dose

• 150mg intramuscularly once daily for 3 consecutive days.

Pediatric Dose

Dosage is determined by the doctor based on the child's weight and severity of the infection.

Elderly

Same as adult dose, but with careful monitoring for side effects.

Administration Instructions

Administered intramuscularly by a healthcare professional.

Common Side Effects

Nausea

Dizziness

Headache

Less Common Side Effects

Injection site pain

Fever

Serious Side Effects

Severe allergic reactions

Heart palpitations

When to Seek Immediate Medical Attention

Difficulty breathing

Swelling of the face, lips, or throat

• Allergy to Arteether — Patients with known hypersensitivity to Arteether should avoid this medication.
• Severe Liver Impairment — Not recommended for patients with significant liver dysfunction.

Drug-Drug Interactions

Quinine

Other antimalarial drugs

Food Interactions

No significant food interactions known.

Alcohol Interactions

Avoid alcohol to reduce side effects.

Disease Interactions

Liver disease

Heart disease

Store at room temperature (15-25°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check the expiry date before use.