Zexone SB 250mg/125mg Injection

by Solace Biotech Ltd · Injection Schedule H
Generic Name Ceftriaxone and Sulbactam
Drug Class Antibiotic
Route Intravenous
Habit Forming No
Prescription Required (Rx)
Strengths 250mg/125mg
MRP
₹42.50
vial of 5 ml Injection

About Zexone SB 250mg/125mg Injection

Zexone SB 250mg/125mg Injection is a combination antibiotic used to treat various bacterial infections. It contains two active ingredients: ceftriaxone, which fights bacteria, and sulbactam, which helps prevent bacteria from breaking down the antibiotic. This medicine is typically used in hospitals for serious infections and is given by a healthcare professional.

Clinical Uses

  • Pneumonia — A lung infection causing cough and difficulty breathing.
  • Urinary Tract Infections — Infections affecting the bladder and kidneys.
  • Skin Infections — Infections affecting the skin and soft tissues.
  • Sepsis — A severe infection that spreads throughout the body.

Uses & Indications

Primary Uses

  • Pneumonia — Effective in treating lung infections caused by bacteria.
  • Urinary Tract Infections — Helps in managing infections in the urinary system.

Secondary Uses

  • Skin Infections — Treats bacterial infections on the skin.
  • Sepsis — Used in severe cases of systemic infection.

How It Works (Mechanism of Action)

Zexone SB works by killing bacteria that cause infections. Ceftriaxone disrupts the formation of the bacterial cell wall, leading to cell death. Sulbactam helps ceftriaxone remain effective against bacteria that produce enzymes to resist antibiotics.

This combination allows for effective treatment of serious infections, especially those caused by resistant bacteria. The two components work together to enhance the overall effectiveness of the treatment.

Key Benefits

  • Broad-Spectrum Activity — Works against a wide range of bacteria.
  • Enhanced Effectiveness — Sulbactam protects ceftriaxone from being broken down by bacteria.
  • Rapid Action — Starts working quickly to reduce infection symptoms.

How Long Does It Take to Work?

Initial improvement may be seen within a few days of starting treatment. The typical full treatment duration is usually 7 to 14 days, depending on the infection. If there is no improvement after a few days, contact your doctor for further evaluation.

How to Use

Consult your healthcare provider for the correct dosage.

The injection will be given by a healthcare professional.

Do not self-administer the injection.

Follow all instructions provided by your healthcare provider.

Dosage Guidelines

Adult Dose

The usual adult dose is determined by the healthcare provider based on the type and severity of the infection.

Pediatric Dose

Dosage for children is also determined by a healthcare provider.

Elderly

Elderly

  • patients may require adjusted doses based on kidney function.

Administration Instructions

Administered by injection into a vein or muscle by a healthcare professional.

Missed Dose

If you miss a dose, contact your healthcare provider for instructions. Do not double the dose to make up for a missed one.

Overdose Warning

Overdose symptoms may include severe allergic reactions or gastrointestinal issues. If you suspect an overdose, seek immediate medical attention or call emergency services.

Side Effects

Common Side Effects

Nausea

Diarrhea

Rash

Less Common Side Effects

Headache

Dizziness

Serious Side Effects

Severe allergic reactions

Clostridium difficile infection

When to Seek Immediate Medical Attention

If you experience difficulty breathing, swelling of the face or throat, or severe diarrhea, seek medical help right away.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Ceftriaxone — Patients with a known allergy should not use this medicine.
  • Allergy to Sulbactam — Avoid use in patients allergic to sulbactam.

Warnings & Precautions

🤰 Pregnancy
Ceftriaxone is classified as a pregnancy category B drug. It is generally considered safe during pregnancy, but always consult your doctor before use.
🤱 Breastfeeding
Ceftriaxone is excreted in breast milk in small amounts. Consult your doctor before using this medication while breastfeeding.
👶 Children
Safety and effectiveness in children depend on the specific condition being treated. Dosage must be determined by a healthcare provider.
🧓 Elderly
Elderly patients may be more sensitive to the effects of this medication. Dosage adjustments may be necessary.
🫘 Kidney Disease
Use with caution in patients with kidney impairment. Dose adjustments may be needed based on kidney function.
🫁 Liver Disease
Use with caution in patients with liver impairment. Monitor liver function during treatment.
🍷 Alcohol
Avoid alcohol while using this medication, as it may increase the risk of side effects.
🚗 Driving
This medication may cause dizziness; use caution when driving or operating machinery.

Drug Interactions

Drug-Drug Interactions

Avoid using with other antibiotics unless prescribed.

May interact with blood thinners; consult your doctor.

Food Interactions

No significant food interactions are known.

Alcohol Interactions

Avoid alcohol while taking this medication.

Disease Interactions

Use with caution in patients with kidney or liver disease.

Storage Instructions

Store at room temperature.

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check expiry date before use.

Expert Advice

Clinical Tips

Complete the full course of treatment as prescribed.

Do not share this medication with others.

Inform your doctor of any allergies.

Report any unusual side effects immediately.

Keep all follow-up appointments with your healthcare provider.

Maintain good hydration during treatment.

Do not stop taking the medication without consulting your doctor.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

Last Updated19 Jun 2026
Content Generated19 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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