Zexpar SL 1000mg/500mg Injection

by Medivista Lifesciences Pvt. Ltd. · Injection Schedule H
Generic Name Sulbactam and Cefoperazone
Drug Class Antibiotic
Route Intravenous
Habit Forming No
Prescription Required (Rx)
Strengths 1000mg/500mg
MRP
₹272.00
vial of 1 Injection

About Zexpar SL 1000mg/500mg Injection

Zexpar SL 1000mg/500mg Injection is a combination antibiotic used to treat various bacterial infections. It contains two active ingredients: Sulbactam and Cefoperazone. This medicine is typically used in hospitals for serious infections, especially when other antibiotics may not be effective. It is important to use this medication under the guidance of a healthcare professional.

Clinical Uses

  • Severe Infections — Effective against serious bacterial infections.
  • Respiratory Tract Infections — Treats infections in the lungs and airways.
  • Urinary Tract Infections — Used for infections in the urinary system.
  • Skin Infections — Helps in treating bacterial skin infections.

Uses & Indications

Primary Uses

  • Severe Infections — Used for serious infections that require immediate treatment.
  • Respiratory Tract Infections — Treats infections like pneumonia and bronchitis.

Secondary Uses

  • Urinary Tract Infections — Effective for infections in the bladder and kidneys.
  • Skin Infections — Helps in managing infections on the skin.

How It Works (Mechanism of Action)

Zexpar SL works by combining two antibiotics that target bacteria. Sulbactam helps prevent bacteria from breaking down Cefoperazone, allowing it to work more effectively. This combination helps to kill bacteria and stop their growth.

Cefoperazone is a type of cephalosporin antibiotic that disrupts the formation of the bacterial cell wall. This action leads to the death of the bacteria, making it effective against various infections. Sulbactam, a beta-lactamase inhibitor, protects Cefoperazone from being destroyed by certain bacteria that produce enzymes to resist antibiotics.

Key Benefits

  • Broad Spectrum — Works against a wide range of bacteria.
  • Combines Two Antibiotics — Enhances effectiveness against resistant bacteria.
  • Fast Acting — Provides quick relief from severe infections.

How Long Does It Take to Work?

You may start to feel better within a few days of starting treatment. However, it is important to complete the full course as prescribed by your doctor, which usually lasts for 7 to 14 days. If you do not see improvement after a few days, contact your healthcare provider.

How to Use

Ensure the injection is prepared by a healthcare professional.

Receive the injection in a hospital or clinic setting.

Follow the prescribed dosage and schedule given by your doctor.

Do not self-administer the injection.

Dosage Guidelines

Adult Dose

The typical adult dose is determined by the severity of the infection and the doctor's recommendation.

Pediatric Dose

Use in children should be determined by a healthcare professional.

Elderly

Elderly

  • patients may require dose adjustments based on their health status.

Administration Instructions

Administered as an injection by a healthcare professional.

Missed Dose

If you miss a dose, contact your healthcare provider for instructions. Do not double the dose to make up for a missed one.

Overdose Warning

Overdose may lead to severe side effects. Symptoms can include confusion, seizures, or severe allergic reactions. If you suspect an overdose, seek immediate medical help or call emergency services.

Side Effects

Common Side Effects

Nausea

Diarrhea

Rash

Less Common Side Effects

Headache

Dizziness

Serious Side Effects

Allergic reactions

Severe diarrhea

When to Seek Immediate Medical Attention

If you experience difficulty breathing, swelling of the face or throat, or severe abdominal pain, seek medical help immediately.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Penicillins — May cause severe allergic reactions.
  • Severe Liver Disease — Can worsen liver function.

Warnings & Precautions

🤰 Pregnancy
Zexpar SL is classified as a Category B medication, which means it is generally considered safe during pregnancy. However, always consult your doctor before use.
🤱 Breastfeeding
It is not known if Zexpar SL passes into breast milk. Consult your doctor before using this medication while breastfeeding.
👶 Children
The safety and effectiveness in children have not been fully established. Always consult a healthcare provider for appropriate dosing.
🧓 Elderly
Elderly patients may have different responses to this medication. Dose adjustments may be necessary based on their overall health.
🫘 Kidney Disease
Use with caution in patients with kidney problems. Dose adjustments may be needed based on kidney function.
🫁 Liver Disease
Use with caution in patients with liver impairment. Dose adjustments may be necessary depending on liver function.
🍷 Alcohol
Avoid alcohol while using this medication as it may increase the risk of side effects.
🚗 Driving
Zexpar SL may cause dizziness; use caution when driving or operating machinery.

Drug Interactions

Drug-Drug Interactions

Avoid using with other antibiotics unless prescribed.

Consult your doctor if you are taking blood thinners.

Food Interactions

No specific food interactions are known.

Alcohol Interactions

Avoid alcohol as it may increase side effects.

Disease Interactions

Use with caution in patients with liver or kidney disease.

Storage Instructions

Store at room temperature.

Keep away from moisture.

Protect from light.

Keep away from children.

Check expiry date before use.

Expert Advice

Clinical Tips

Complete the full course of treatment as prescribed.

Do not share this medication with others.

Report any unusual side effects to your doctor.

Keep all follow-up appointments with your healthcare provider.

Stay hydrated while on this medication.

Inform your doctor about any other medications you are taking.

Do not stop taking the medication without consulting your doctor.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

Last Updated22 Jun 2026
Content Generated22 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
Scroll to Top