Ziclofenac 75mg Injection

by Zenicure Labs · Injection Schedule H
Generic Name Diclofenac
Drug Class Nonsteroidal Anti-inflammatory Drug (NSAID)
Route Intramuscular
Habit Forming No
Prescription Required (Rx)
Strengths 75mg
MRP
₹22.00
ampoule of 1 ml Injection

About Ziclofenac 75mg Injection

Ziclofenac 75mg Injection contains Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and reduce inflammation. It is commonly used for conditions like arthritis, muscle pain, and postoperative pain. This medication is administered via intramuscular injection and should be used under medical supervision. It is important for patients to follow their healthcare provider's instructions and report any side effects.

Clinical Uses

  • Arthritis — Helps reduce inflammation and pain in joints.
  • Muscle Pain — Provides relief from muscle aches and discomfort.
  • Postoperative Pain — Used to manage pain after surgery.

Uses & Indications

Primary Uses

Relief of pain and inflammation in conditions like arthritis.

Management of acute musculoskeletal pain.

Secondary Uses

Postoperative pain relief.

Off-label Uses

Not commonly used off-label.

How It Works (Mechanism of Action)

Diclofenac works by reducing substances in the body that cause pain and inflammation. It blocks the production of prostaglandins, chemicals responsible for inflammation, pain, and fever.

Scientifically, Diclofenac inhibits the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins. By blocking COX, Diclofenac reduces the formation of inflammatory mediators, leading to decreased inflammation and pain.

Key Benefits

Reduces inflammation and swelling.

Provides effective pain relief.

Improves mobility in patients with arthritis.

How Long Does It Take to Work?

Initial pain relief can be felt within 30 minutes to 1 hour after administration. Full therapeutic effects may take a few days of consistent use. If there is no improvement in symptoms after a few days, consult your doctor.

How to Use

Ensure the injection is administered by a healthcare professional.

Follow the prescribed dosage and schedule.

Do not self-administer unless instructed by a healthcare provider.

Dosage Guidelines

Adult Dose

Typically, 75mg once or twice daily as needed.

Pediatric Dose

Not recommended for children.

Elderly

Use with caution and under medical supervision.

Administration Instructions

Administer via intramuscular injection.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double the dose to catch up.

Overdose Warning

In case of overdose, symptoms may include nausea, vomiting, stomach pain, dizziness, or drowsiness. Seek immediate medical attention or contact poison control.

Side Effects

Common Side Effects

Nausea

Headache

Dizziness

Less Common Side Effects

Rash

Swelling at the injection site

Serious Side Effects

Severe stomach pain

Difficulty breathing

When to Seek Immediate Medical Attention

Signs of an allergic reaction such as rash, itching, or swelling.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Diclofenac — Do not use if you have a known allergy.
  • Active Peptic Ulcer — May worsen the condition.
  • Severe Liver or Kidney Disease — Use is contraindicated.

Warnings & Precautions

🤰 Pregnancy
Pregnancy Category C. Use only if clearly needed and prescribed by a doctor. Avoid use in the third trimester due to potential harm to the fetus.
🤱 Breastfeeding
Diclofenac may pass into breast milk. Consult your doctor before use if you are breastfeeding.
👶 Children
Not recommended for use in children due to lack of safety data.
🧓 Elderly
Use with caution in elderly patients. Dosage adjustments may be necessary due to increased risk of side effects.
🫘 Kidney Disease
Use with caution in patients with renal impairment. Dose adjustment may be required.
🫁 Liver Disease
Use with caution in patients with liver impairment. Dose adjustment may be necessary.
❤️ Heart Disease
Use with caution in patients with heart disease as NSAIDs may increase the risk of cardiovascular events.
💉 Diabetes
No specific warnings for diabetic patients, but monitor blood sugar levels as NSAIDs can affect renal function.
🩸 Hypertension
Use with caution in patients with hypertension as NSAIDs can cause fluid retention and increase blood pressure.
🍷 Alcohol
Avoid alcohol as it may increase the risk of stomach bleeding with NSAIDs.
🚗 Driving
Diclofenac may cause dizziness; avoid driving if you feel dizzy.

Drug Interactions

Drug-Drug Interactions

Aspirin

Other NSAIDs

Blood thinners like Warfarin

Food Interactions

Take with food to reduce stomach upset.

Alcohol Interactions

Avoid alcohol to reduce the risk of stomach bleeding.

Disease Interactions

Peptic Ulcer Disease

Kidney Disease

Storage Instructions

Store at room temperature.

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check expiry date before use.

Expert Advice

Clinical Tips

Complete the full course as prescribed.

Report any unusual symptoms to your doctor.

Do not share your medication with others.

Inform your doctor about all other medications you are taking.

Do not use if you have a history of allergic reactions to NSAIDs.

Monitor for signs of stomach bleeding.

Stay hydrated and avoid alcohol.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Frequently Asked Questions

What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule.
Can I take Ziclofenac with other pain relievers?
Consult your healthcare provider before taking Ziclofenac with other pain relievers to avoid potential interactions.
How long can I use Ziclofenac?
The duration of treatment with Ziclofenac should be determined by your healthcare provider based on your specific condition.

Sources

The information on this page about Ziclofenac 75mg Injection has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.

  1. Manufacturer – Ziclofenac 75mg Injection Prescribing Information and Product Monograph
  2. NHSDiclofenac: Overview
  3. Mayo ClinicDiclofenac (Oral Route, Injection Route)
  4. MedlinePlusDiclofenac Injection
  5. DailyMedDiclofenac Sodium Injection
Last Updated10 Jun 2026
Content Generated10 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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