Zidovex 300mg Capsule

by Veritaz Healthcare Ltd · Capsule Schedule H
Generic Name Zidovudine
Drug Class Antiretroviral
Route Oral
Habit Forming No
Prescription Required (Rx)
Strengths 300mg
MRP
₹259.56
strip of 10 capsules

About Zidovex 300mg Capsule

Zidovex 300mg Capsule contains Zidovudine, an antiretroviral medication used to treat HIV infection. It helps to control the infection and improve the immune system by reducing the amount of virus in the body. This medicine is typically used in combination with other antiretroviral drugs. Zidovex is prescribed to both adults and children who are infected with HIV. It is important for patients to follow their healthcare provider's instructions carefully and not to stop taking the medication without consulting their doctor.

Clinical Uses

  • HIV Infection — Used in combination with other antiretroviral agents to treat HIV-1 infection.

Uses & Indications

Primary Uses

HIV treatment in combination with other antiretrovirals.

Secondary Uses

Off-label Uses

How It Works (Mechanism of Action)

Zidovex 300mg Capsule works by inhibiting the replication of the HIV virus in the body. It reduces the amount of virus, which helps to improve the immune system and decrease the risk of developing HIV-related complications.

Scientifically, Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI). It incorporates into the viral DNA chain and causes chain termination, thereby preventing the virus from multiplying.

Key Benefits

  • Reduces Viral Load — Helps in lowering the amount of HIV in the body.
  • Improves Immune Function — Aids in boosting the immune system to fight infections.
  • Delays Disease Progression — Slows down the progression of HIV-related illnesses.

How Long Does It Take to Work?

Initial improvement in symptoms may be observed within a few weeks of starting treatment. However, full therapeutic effects may take several months. If there is no improvement or if symptoms worsen, consult your doctor.

How to Use

Take Zidovex 300mg Capsule exactly as prescribed by your doctor.

Swallow the capsule whole with a glass of water.

It can be taken with or without food.

Do not crush or chew the capsule.

Maintain a regular schedule to ensure consistent blood levels of the medication.

Dosage Guidelines

Adult Dose

Typically, 300mg twice daily in combination with other antiretrovirals.

Pediatric Dose

Dosing is based on body weight and should be determined by a pediatrician.

Elderly

Use with caution and under medical supervision.

Administration Instructions

Follow the prescribed schedule and do not alter the dose without consulting your doctor.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Overdose Warning

In case of an overdose, symptoms may include nausea, vomiting, headache, and fatigue. Seek immediate medical attention or contact poison control for guidance.

Side Effects

Common Side Effects

Nausea

Headache

Fatigue

Less Common Side Effects

Dizziness

Diarrhea

Serious Side Effects

Severe anemia

Lactic acidosis

When to Seek Immediate Medical Attention

Signs of an allergic reaction such as rash, itching, or swelling.

Difficulty breathing or swallowing.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Zidovudine — Patients with known hypersensitivity should not use this medication.
  • Severe Liver Disease — Not recommended for patients with significant liver impairment.

Warnings & Precautions

🤰 Pregnancy
Pregnancy Category C. Zidovex should be used during pregnancy only if clearly needed and prescribed by a doctor. Discuss potential risks and benefits with your healthcare provider.
🤱 Breastfeeding
Zidovudine can pass into breast milk. HIV-infected mothers are advised not to breastfeed to prevent transmission of the virus to the infant.
👶 Children
Zidovex can be used in children under medical supervision, with dosage based on body weight.
🧓 Elderly
Elderly patients may require dose adjustments and should be monitored for side effects.
🫘 Kidney Disease
Use with caution in patients with renal impairment. Dose adjustment may be necessary.
🫁 Liver Disease
Patients with liver impairment should use Zidovex with caution, and dose adjustments may be needed.
💉 Diabetes
Diabetic patients should monitor blood sugar levels as Zidovex may affect glucose metabolism.
🍷 Alcohol
Alcohol may increase the risk of liver damage and should be avoided while taking Zidovex.
🚗 Driving
Zidovex may cause dizziness, so avoid driving or operating heavy machinery if affected.

Drug Interactions

Drug-Drug Interactions

Stavudine

Ribavirin

Food Interactions

No significant food interactions.

Alcohol Interactions

Avoid alcohol to prevent liver damage.

Disease Interactions

Liver disease

Kidney disease

Storage Instructions

Store at room temperature (15-25°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check expiry date before use.

Expert Advice

Clinical Tips

Complete the full course of treatment as prescribed.

Do not share your medication with others.

Inform your doctor about all other medications you are taking.

Regular blood tests may be required to monitor your condition.

Report any unusual side effects to your doctor immediately.

Avoid alcohol to reduce the risk of liver damage.

Maintain a healthy diet and lifestyle to support your treatment.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Frequently Asked Questions

How long do I need to take Zidovex?
The duration of treatment with Zidovex will depend on your healthcare provider's recommendations and your individual health needs.
Can I stop taking Zidovex if I feel better?
No, it is important to continue taking Zidovex as prescribed, even if you feel better, to effectively manage HIV.
What should I do if I miss a dose?
If you miss a dose of Zidovex, take it as soon as you remember, but skip it if it's almost time for your next dose. Do not double up.

Sources

The information on this page about Zidovex 300mg Capsule has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.

  1. Manufacturer – Zidovex 300mg Capsule Prescribing Information and Product Monograph
  2. NHSZidovudine: Overview and Uses
  3. MedlinePlusZidovudine
  4. DailyMedZidovudine Capsule, USP
  5. DrugBankZidovudine
Last Updated12 Jun 2026
Content Generated12 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
Scroll to Top