Ziofen RZ 200mg/20mg Capsule

by Ziotic Life Sciences · Capsule Rx
Generic Name Aceclofenac and Rabeprazole
Drug Class Non-steroidal anti-inflammatory drug (NSAID) and Proton Pump Inhibitor (PPI)
Route Oral
Habit Forming No
Prescription Required (Rx)
Strengths 200mg/20mg
MRP
₹98.00
strip of 10 capsules

About Ziofen RZ 200mg/20mg Capsule

Ziofen RZ 200mg/20mg Capsule is a combination medicine that contains Aceclofenac and Rabeprazole. It is primarily used to relieve pain and inflammation, especially in conditions like arthritis. The Rabeprazole component helps protect the stomach from irritation caused by Aceclofenac. This medicine is suitable for adults who need pain relief while minimizing stomach-related side effects.

Clinical Uses

  • Arthritis — Reduces pain and inflammation in joint disorders.
  • Musculoskeletal Pain — Alleviates pain from muscle and bone injuries.

Uses & Indications

Primary Uses

  • Arthritis — To relieve pain and inflammation associated with arthritis.
  • Musculoskeletal Pain — To manage pain from injuries or conditions affecting muscles and bones.

Secondary Uses

  • Dyspepsia — To help manage stomach discomfort related to pain medications.

How It Works (Mechanism of Action)

Ziofen RZ works by combining two active ingredients. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation by blocking certain chemicals in the body. Rabeprazole is a proton pump inhibitor (PPI) that decreases stomach acid production, helping to prevent irritation caused by NSAIDs.

This combination allows patients to manage pain effectively while minimizing the risk of stomach-related side effects that can occur with NSAIDs alone.

Key Benefits

  • Pain Relief — Effectively reduces pain from various conditions.
  • Anti-inflammatory — Decreases inflammation, helping with swelling and discomfort.
  • Stomach Protection — Rabeprazole helps protect the stomach lining from irritation.

How Long Does It Take to Work?

Initial improvement in pain may be noticed within a few days of starting treatment. Full benefits may take longer, typically a few weeks. If there is no improvement after two weeks, consult your doctor.

How to Use

Take the capsule with a full glass of water.

Do not chew or crush the capsule.

Follow your doctor's prescribed dosage.

Take it at the same time each day for best results.

Dosage Guidelines

Adult Dose

One capsule daily, or as directed by your doctor.

Pediatric Dose

Not recommended for children.

Elderly

Use with caution; consult your doctor for appropriate dosing.

Administration Instructions

Take with food to reduce stomach irritation.

Missed Dose

If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Overdose Warning

Overdose symptoms may include nausea, vomiting, and stomach pain. If you suspect an overdose, seek immediate medical attention or contact poison control.

Side Effects

Common Side Effects

Nausea

Stomach pain

Headache

Less Common Side Effects

Diarrhea

Dizziness

Serious Side Effects

Allergic reactions

Severe stomach pain

When to Seek Immediate Medical Attention

If you experience severe allergic reactions, chest pain, or significant stomach issues, seek medical help right away.

Contraindications — Who Should Not Use This Medicine

  • Allergy to NSAIDs — Risk of severe allergic reactions.
  • Active Stomach Ulcer — Increased risk of bleeding and irritation.
  • Severe Liver Disease — May worsen liver function.

Warnings & Precautions

🤰 Pregnancy
This medicine is generally not recommended during pregnancy, especially in the third trimester. Consult your doctor before use.
🤱 Breastfeeding
It is not known if this medicine passes into breast milk. Consult your doctor before using it while breastfeeding.
👶 Children
Ziofen RZ is not recommended for children. Consult a doctor for appropriate alternatives.
🧓 Elderly
Elderly patients should use this medicine with caution. Dosage adjustments may be necessary based on individual health conditions.
🫘 Kidney Disease
Use with caution in patients with kidney impairment. Dose adjustments may be needed based on kidney function.
🫁 Liver Disease
Use with caution in patients with liver impairment. Consult your doctor for appropriate dosing.
🍷 Alcohol
Avoid alcohol while taking this medicine, as it can increase the risk of stomach irritation.
🚗 Driving
This medicine may cause dizziness; use caution when driving or operating machinery.

Drug Interactions

Drug-Drug Interactions

Aspirin

Other NSAIDs

Blood thinners

Food Interactions

Taking with food can help reduce stomach irritation.

Alcohol Interactions

Avoid alcohol to minimize stomach irritation.

Disease Interactions

Use with caution in patients with a history of stomach ulcers or liver disease.

Storage Instructions

Store at room temperature.

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check the expiry date before use.

Expert Advice

Clinical Tips

Take the medicine exactly as prescribed by your doctor.

Do not share your medication with others.

Complete the full course of treatment.

Keep track of any side effects and report them to your doctor.

Do not stop taking the medicine suddenly without consulting your doctor.

Stay hydrated while taking this medication.

Inform your doctor about any other medications you are taking.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

Last Updated22 Jun 2026
Content Generated22 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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