Ziomi 15mg/10mg Capsule

by Aanika Pharma · Capsule Schedule H
Generic Name Domperidone, Omeprazole
Drug Class Prokinetic agent and Proton pump inhibitor
Route Oral
Habit Forming No
Prescription Required (Rx)
Strengths 15mg/10mg
MRP
₹49.90
strip of 20 capsules

About Ziomi 15mg/10mg Capsule

Ziomi 15mg/10mg Capsule is a combination medication containing Domperidone and Omeprazole. It is used to treat conditions such as gastroesophageal reflux disease (GERD) and other related digestive issues. Domperidone helps in improving the movement of the stomach and intestines, while Omeprazole reduces stomach acid production. This medicine is typically prescribed for adults and should be used under medical supervision. It is important for patients to follow their healthcare provider's instructions for optimal results.

Clinical Uses

  • Gastroesophageal Reflux Disease (GERD) — A condition where stomach acid frequently flows back into the esophagus.
  • Indigestion — Discomfort or pain in the stomach associated with difficulty in digesting food.
  • Nausea and Vomiting — Symptoms often associated with digestive disturbances.

Uses & Indications

Primary Uses

Relief from symptoms of gastroesophageal reflux disease (GERD).

Treatment of indigestion and heartburn.

Prevention of nausea and vomiting associated with certain conditions.

Secondary Uses

Management of symptoms in patients with peptic ulcer disease.

Off-label Uses

Not typically used for off-label purposes.

How It Works (Mechanism of Action)

Ziomi 15mg/10mg Capsule works by combining the effects of Domperidone and Omeprazole. Domperidone increases the movements of the stomach and intestines, which helps in faster gastric emptying. Omeprazole reduces the amount of acid produced in the stomach, providing relief from acid-related indigestion and heartburn.

Domperidone is a dopamine antagonist that works on the chemoreceptor trigger zone in the brain, reducing nausea and vomiting. Omeprazole is a proton pump inhibitor that blocks the final step of acid production in the stomach lining, thereby reducing gastric acidity and promoting healing of ulcers.

Key Benefits

  • Reduces Stomach Acid — Helps in alleviating symptoms of acid reflux and heartburn.
  • Improves Gastric Motility — Enhances the movement of food through the stomach and intestines.
  • Prevents Nausea and Vomiting — Effective in controlling nausea and vomiting associated with digestive issues.

How Long Does It Take to Work?

Initial improvement in symptoms can be observed within a few hours of taking the capsule. Full therapeutic effects may take several days to manifest. If there is no improvement in symptoms after two weeks of use, consult your doctor for further evaluation.

How to Use

Take the capsule as prescribed by your doctor, usually once daily before a meal.

Swallow the capsule whole with a glass of water. Do not crush or chew the capsule.

Follow the dosage schedule as advised by your healthcare provider.

Continue taking the medication even if you feel better, unless instructed otherwise by your doctor.

Dosage Guidelines

Adult Dose

Typically, one capsule taken once daily before a meal.

Pediatric Dose

Not recommended for children.

Elderly

Use with caution and under medical supervision.

Administration Instructions

Take the capsule before meals for optimal effect.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

Overdose Warning

In case of an overdose, symptoms may include dizziness, confusion, and irregular heartbeat. Seek immediate medical attention or contact a poison control center if an overdose is suspected.

Side Effects

Common Side Effects

Headache

Diarrhea

Dry mouth

Less Common Side Effects

Abdominal pain

Dizziness

Serious Side Effects

Allergic reactions such as rash, itching, or swelling

Severe dizziness or trouble breathing

When to Seek Immediate Medical Attention

If you experience signs of an allergic reaction or severe side effects.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Domperidone or Omeprazole — Patients with known hypersensitivity should not use this medication.
  • Severe Liver Impairment — Use is contraindicated in patients with significant liver dysfunction.
  • Prolactinoma — Patients with pituitary tumors should avoid this medicine.

Warnings & Precautions

🤰 Pregnancy
Category C: Use only if clearly needed and prescribed by a doctor. Discuss potential risks and benefits with your healthcare provider.
🤱 Breastfeeding
Domperidone is excreted in breast milk in small amounts. Consult your doctor before using this medication while breastfeeding.
👶 Children
Not recommended for use in children as safety and efficacy have not been established.
🧓 Elderly
Use with caution in elderly patients. Dose adjustments may be necessary based on individual health conditions.
🫘 Kidney Disease
Patients with renal impairment should use this medication with caution. Dose adjustments may be required.
🫁 Liver Disease
Use with caution in patients with liver impairment. Regular monitoring and dose adjustments may be necessary.
❤️ Heart Disease
Patients with heart conditions should use this medication with caution due to potential cardiac side effects.
💉 Diabetes
There are no known interactions with diabetes medications, but monitor blood sugar levels regularly.
🍷 Alcohol
Avoid alcohol as it can increase stomach acid production and worsen symptoms.
🚗 Driving
This medication may cause dizziness. Avoid driving or operating heavy machinery if you feel drowsy.

Drug Interactions

Drug-Drug Interactions

Ketoconazole

Erythromycin

Warfarin

Food Interactions

Take before meals for best results.

Alcohol Interactions

Avoid alcohol as it may increase side effects.

Disease Interactions

Heart disease

Liver impairment

Storage Instructions

Store at room temperature (15-30°C).

Keep away from moisture and direct sunlight.

Keep out of reach of children.

Check the expiry date before use.

Expert Advice

Clinical Tips

Complete the full course of medication as prescribed.

Do not crush or chew the capsule.

Take the medication before meals for best results.

Avoid alcohol while taking this medication.

Consult your doctor if symptoms persist or worsen.

Inform your doctor about any other medications you are taking.

Report any unusual side effects to your healthcare provider.

Do not share your medication with others.

Store the medication properly to maintain its efficacy.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Frequently Asked Questions

Can I take Ziomi with other medications?
Always consult your healthcare provider before taking Ziomi with other medications to avoid potential interactions.
How long can I take Ziomi?
The duration of treatment should be determined by your healthcare provider based on your specific condition.
What should I do if I miss a dose?
If you miss a dose of Ziomi, take it as soon as you remember, but skip it if it's almost time for your next dose. Do not double the dose.

Sources

The information on this page about Ziomi 15mg/10mg Capsule has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.

  1. Manufacturer – Ziomi 15mg/10mg Capsule Prescribing Information and Product Monograph
  2. NHSDomperidone: Overview and Usage
  3. Mayo ClinicOmeprazole: Uses and Side Effects
  4. MedlinePlusOmeprazole: MedlinePlus Drug Information
  5. DrugBankDomperidone: DrugBank Information
Last Updated10 Jun 2026
Content Generated10 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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