Zivudin 300mg Tablet

Zivudin 300mg Tablet contains Zidovudine, an antiretroviral medication used to treat HIV infection. It helps to control the infection and improve the immune system by reducing the amount of virus in the body. This medicine is usually prescribed as part of a combination therapy for HIV. Patients should take it exactly as prescribed by their healthcare provider. It is important for individuals with HIV to adhere to their treatment regimen to prevent the progression of the disease and transmission to others.

• HIV Infection — Used in combination with other antiretrovirals to treat HIV-1 infection.

Primary Uses

HIV Treatment

Secondary Uses

Prevention of maternal-fetal HIV transmission

Off-label Uses

Zidovudine works by inhibiting the action of reverse transcriptase, an enzyme that HIV needs to multiply. This helps reduce the amount of virus in the body, allowing the immune system to function better.

Scientifically, Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI). It incorporates itself into the viral DNA chain and causes chain termination, preventing the virus from replicating effectively.

• Reduces Viral Load — Helps decrease the amount of HIV in the blood.
• Improves Immune Function — Supports the immune system in fighting infections.
• Prevents Disease Progression — Slows down the progression of HIV-related diseases.

Initial improvement in symptoms may be noticed within a few weeks of starting treatment. Full therapeutic effects can take several months. If there is no improvement or if symptoms worsen, consult your doctor.

Take the tablet by mouth with or without food.

Swallow the tablet whole with a glass of water.

Follow the dosing schedule as prescribed by your doctor.

Do not skip doses to ensure effectiveness.

Continue taking the medication even if you feel well.

Adult Dose

• 300mg twice daily in combination with other antiretrovirals.

Pediatric Dose

Dosage is based on body weight and should be determined by a doctor.

Elderly

Same as adult dose, but close monitoring is required.

Administration Instructions

Take at the same time each day to maintain consistent blood levels.

Common Side Effects

Headache

Nausea

Fatigue

Less Common Side Effects

Muscle pain

Insomnia

Serious Side Effects

Anemia

Lactic acidosis

When to Seek Immediate Medical Attention

Signs of an allergic reaction like rash, itching, or swelling

Severe fatigue or weakness

• Allergy to Zidovudine — Patients with known hypersensitivity should not use this medication.
• Severe Liver Disease — Not recommended due to potential for increased toxicity.

Drug-Drug Interactions

Ribavirin

Stavudine

Ganciclovir

Food Interactions

No significant food interactions.

Alcohol Interactions

Avoid alcohol to prevent liver damage.

Disease Interactions

Liver disease

Kidney disease

Store at room temperature (15-25°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check the expiry date before use.