Zomika 500mg Injection

by Zota Pharmaceuticals Pvt Ltd · Injection Schedule H
Generic Name Amikacin
Drug Class Aminoglycoside antibiotic
Route Intravenous / Intramuscular
Habit Forming No
Prescription Required (Rx)
Strengths 500mg
MRP
₹61.90
vial of 2 ml Injection

About Zomika 500mg Injection

Zomika 500mg Injection contains Amikacin, an antibiotic used to treat serious bacterial infections. It is effective against a variety of bacteria and is often used in hospitals for infections that do not respond to other antibiotics. This medicine is usually given to patients who are hospitalized or have severe infections. It is important to use this medication under the guidance of a healthcare professional to ensure safety and effectiveness.

Clinical Uses

  • Severe Infections — Used for serious infections caused by bacteria.
  • Urinary Tract Infections — Treats infections in the urinary system.
  • Pneumonia — Effective against lung infections.
  • Sepsis — Used in life-threatening infections in the bloodstream.

Uses & Indications

Primary Uses

  • Severe Bacterial Infections — Treats infections that are resistant to other antibiotics.
  • Urinary Tract Infections — Effective for complicated urinary infections.

Secondary Uses

  • Pneumonia — Used for bacterial pneumonia cases.
  • Sepsis — Helps in managing severe infections in the bloodstream.

How It Works (Mechanism of Action)

Amikacin works by stopping the growth of bacteria. It does this by interfering with the bacteria's ability to make proteins, which are essential for their survival and reproduction. By disrupting protein synthesis, Amikacin effectively kills the bacteria causing the infection.

Scientifically, Amikacin binds to the 30S ribosomal subunit of bacteria, leading to misreading of m

RNA. This results in the production of nonfunctional or toxic proteins, ultimately causing cell death. It is particularly effective against aerobic Gram-negative bacteria and some Gram-positive bacteria.

Key Benefits

  • Broad-Spectrum Activity — Works against a wide range of bacteria.
  • Effective in Serious Infections — Crucial for treating life-threatening infections.
  • Rapid Action — Starts working quickly to reduce infection symptoms.

How Long Does It Take to Work?

You may start to feel better within a few days of starting the treatment, but it is important to complete the full course as prescribed by your doctor. The typical duration of treatment can range from 7 to 14 days, depending on the severity of the infection. If you do not see any improvement after a few days, contact your healthcare provider.

How to Use

Wash your hands thoroughly before handling the injection.

Prepare the injection site by cleaning it with an antiseptic wipe.

Administer the injection as directed by your healthcare provider.

Dispose of the needle and syringe safely after use.

Monitor for any side effects and report them to your doctor.

Dosage Guidelines

Adult Dose

The typical dose for adults is 15 mg/kg/day, divided into two or three doses.

Pediatric Dose

For children

  • , the dose is usually based on body weight and should be determined by a healthcare professional.

Elderly

Elderly

  • patients may require dose adjustments based on kidney function.

Administration Instructions

Administer via intramuscular or intravenous route as directed by a healthcare provider.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Overdose Warning

Overdose symptoms may include hearing loss, kidney problems, or muscle weakness. If you suspect an overdose, seek immediate medical attention or call emergency services.

Side Effects

Common Side Effects

Nausea

Vomiting

Diarrhea

Less Common Side Effects

Rash

Fever

Serious Side Effects

Hearing loss

Kidney damage

When to Seek Immediate Medical Attention

If you experience severe allergic reactions, difficulty breathing, or signs of kidney problems, seek medical help right away.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Amikacin — Patients with known hypersensitivity should not use this medication.
  • Severe Kidney Disease — Not recommended for patients with significant renal impairment.

Warnings & Precautions

🤰 Pregnancy
Amikacin is classified as a Category D medication, meaning it may pose risks to the fetus. It should only be used during pregnancy if absolutely necessary and prescribed by a healthcare provider.
🤱 Breastfeeding
Amikacin may pass into breast milk, but it is generally considered safe for breastfeeding mothers. However, consult your doctor before use.
👶 Children
Amikacin can be used in children, but the dosage must be carefully calculated based on their weight. Always consult a pediatrician for appropriate dosing.
🧓 Elderly
Elderly patients may be more sensitive to the effects of Amikacin. Dose adjustments may be necessary based on kidney function.
🫘 Kidney Disease
Amikacin should be used with caution in patients with kidney impairment. Dose adjustments may be required to prevent toxicity.
🫁 Liver Disease
There are no specific warnings for liver impairment, but caution is advised. Consult your doctor for any liver-related concerns.
🍷 Alcohol
Avoid alcohol while using Amikacin, as it may increase the risk of side effects.
🚗 Driving
Amikacin does not typically affect your ability to drive or operate machinery.

Drug Interactions

Drug-Drug Interactions

Avoid using with other nephrotoxic drugs (e.g., certain diuretics).

May interact with other antibiotics.

Food Interactions

No significant food interactions are known.

Alcohol Interactions

Alcohol may increase the risk of side effects.

Disease Interactions

Use with caution in patients with kidney disease.

Storage Instructions

Store at room temperature (15-30°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check expiry date before use.

Expert Advice

Clinical Tips

Complete the full course of treatment as prescribed.

Do not share this medication with others.

Monitor for any side effects and report them to your doctor.

Stay hydrated while on this medication.

Do not stop the medication early, even if you feel better.

Inform your doctor about any other medications you are taking.

Follow up with your healthcare provider for any concerns.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

Last Updated19 Jun 2026
Content Generated19 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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