Zomipra D 10mg/20mg Capsule

by Aspo Healthcare · Capsule Rx
Generic Name Domperidone and Omeprazole
Drug Class Antiemetic and Proton Pump Inhibitor
Route Oral
Habit Forming No
Prescription Required (Rx)
Strengths 10mg/20mg
MRP
₹105.00
strip of 15 capsules

About Zomipra D 10mg/20mg Capsule

Zomipra D 10mg/20mg Capsule is a combination medication that contains Domperidone and Omeprazole. It is used to treat conditions like nausea, vomiting, and gastroesophageal reflux disease (GERD). This medicine helps reduce stomach acid and improve gut movement. It is suitable for adults and children above a certain age, but it is important to use it under the guidance of a healthcare professional.

Clinical Uses

  • Nausea and Vomiting — Helps relieve nausea and vomiting caused by various conditions.
  • Gastroesophageal Reflux Disease (GERD) — Reduces acid reflux and associated symptoms.

Uses & Indications

Primary Uses

  • Nausea and Vomiting — Effective in treating nausea and vomiting due to various causes.
  • Gastroesophageal Reflux Disease (GERD) — Helps manage symptoms of GERD by reducing stomach acid.

Secondary Uses

  • Functional Dyspepsia — May help relieve symptoms of indigestion.

Off-label Uses

  • Gastroparesis — Sometimes used to aid in gastric emptying.

How It Works (Mechanism of Action)

Zomipra D works by combining two active ingredients: Domperidone and Omeprazole. Domperidone helps to increase the movement of the stomach and intestines, which can reduce feelings of nausea and help food move through the digestive system. Omeprazole is a proton pump inhibitor that decreases the amount of acid produced in the stomach, helping to relieve symptoms of acid reflux and heartburn.

The scientific mechanism involves Domperidone blocking dopamine receptors in the gut, which enhances gastric motility and prevents nausea. Omeprazole inhibits the proton pump in the stomach lining, reducing gastric acid secretion. Together, these actions help manage symptoms related to excess stomach acid and gastrointestinal motility disorders.

Key Benefits

  • Reduces Nausea — Helps alleviate feelings of nausea effectively.
  • Improves Digestion — Aids in better digestion by enhancing gut motility.
  • Decreases Stomach Acid — Lowers acid production, providing relief from acid-related discomfort.

How Long Does It Take to Work?

You may start to feel some relief from nausea within 30 minutes to an hour after taking Zomipra D. Full benefits may take a few days of regular use. If you do not notice any improvement after two weeks, consult your doctor for further evaluation.

How to Use

Take the capsule with a full glass of water.

It can be taken with or without food.

Follow the dosage prescribed by your doctor.

Do not chew or crush the capsule.

Take it at the same time each day for best results.

Dosage Guidelines

Adult Dose

Typically, one capsule daily or as directed by your doctor.

Pediatric Dose

Consult a pediatrician for appropriate dosing in children.

Elderly

Dosage may need adjustment; consult your doctor.

Administration Instructions

Swallow the capsule whole with water.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once.

Overdose Warning

In case of overdose, symptoms may include severe drowsiness, confusion, or unusual heart rhythms. Seek immediate medical attention or contact poison control.

Side Effects

Common Side Effects

Nausea

Headache

Dry Mouth

Less Common Side Effects

Diarrhea

Fatigue

Serious Side Effects

Severe Allergic Reactions

Heart Rhythm Changes

When to Seek Immediate Medical Attention

If you experience severe side effects or symptoms of an allergic reaction, seek medical help right away.

Contraindications — Who Should Not Use This Medicine

  • Allergy to Ingredients — Do not use if you are allergic to Domperidone or Omeprazole.
  • Severe Liver Disease — Not recommended for patients with severe liver impairment.
  • Prolactinoma — Should not be used in patients with this pituitary tumor.

Warnings & Precautions

🤰 Pregnancy
Zomipra D is classified as a pregnancy category C medication. It should only be used if the potential benefits outweigh the risks. Consult your doctor before using it during pregnancy.
🤱 Breastfeeding
It is not known if Zomipra D passes into breast milk. Consult your doctor before using this medication while breastfeeding.
👶 Children
Safety and effectiveness in children have not been established. Consult a pediatrician for advice on use in children.
🧓 Elderly
Elderly patients may be more sensitive to the effects of this medication. Dosage may need to be adjusted based on individual health conditions.
🫘 Kidney Disease
Use with caution in patients with kidney impairment. Dose adjustments may be necessary based on kidney function.
🫁 Liver Disease
Caution is advised in patients with liver impairment. Dosage adjustments may be required.
💉 Diabetes
Zomipra D can be used in diabetic patients, but monitoring is recommended.
🍷 Alcohol
Avoid alcohol while taking this medication as it may increase the risk of side effects.
🚗 Driving
Zomipra D may cause dizziness in some patients; use caution when driving or operating machinery.

Drug Interactions

Drug-Drug Interactions

Avoid using with other medications that affect heart rhythm.

Consult your doctor if taking other proton pump inhibitors.

Food Interactions

Food does not significantly affect the absorption of this medication.

Alcohol Interactions

Alcohol may increase the risk of side effects.

Disease Interactions

Use with caution in patients with liver or kidney disease.

Storage Instructions

Store at room temperature.

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check expiry date before use.

Expert Advice

Clinical Tips

Take the medication as prescribed by your doctor.

Do not stop taking it without consulting your healthcare provider.

Keep track of any side effects you experience.

Maintain a healthy diet to support treatment.

Stay hydrated while taking this medication.

Inform your doctor about all other medications you are taking.

Attend regular follow-up appointments to monitor your condition.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

Last Updated23 Jun 2026
Content Generated23 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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