Zotaflam 100mg/325mg Tablet

by Zota Pharmaceuticals Pvt Ltd · Tablet OTC
Generic Name Aceclofenac and Paracetamol
Drug Class Non-steroidal anti-inflammatory drug (NSAID) and analgesic
Route Oral
Habit Forming No
Prescription Not Required
Strengths 100mg/325mg
MRP
₹40.00
strip of 10 tablets

About Zotaflam 100mg/325mg Tablet

Zotaflam 100mg/325mg Tablet is a combination medicine that contains two active ingredients: Aceclofenac and Paracetamol. It is used to relieve pain and reduce inflammation. This medicine is commonly used for conditions like arthritis, muscle pain, and headaches. It is suitable for adults and children over a certain age, but it is important to follow dosing instructions carefully.

Clinical Uses

  • Arthritis — Helps reduce pain and inflammation in joints.
  • Muscle Pain — Provides relief from muscle aches and strains.
  • Headaches — Alleviates mild to moderate headaches.
  • Dental Pain — Eases pain after dental procedures.

Uses & Indications

Primary Uses

  • Arthritis — Reduces joint pain and swelling.
  • Muscle Pain — Alleviates discomfort from muscle injuries.

Secondary Uses

  • Headaches — Helps relieve tension and migraine headaches.
  • Dental Pain — Provides pain relief after dental work.

How It Works (Mechanism of Action)

Zotaflam works by blocking certain chemicals in the body that cause pain and inflammation. This helps to provide relief from various types of pain.

Aceclofenac is an NSAID that inhibits the enzyme cyclooxygenase (COX), leading to decreased production of prostaglandins, which are responsible for pain and inflammation. Paracetamol works primarily in the brain to reduce pain and fever.

Key Benefits

  • Effective Pain Relief — Combines two medications for better pain management.
  • Anti-inflammatory — Reduces swelling and inflammation in the body.
  • Quick Onset — Starts working within a short time to relieve pain.

How Long Does It Take to Work?

Initial improvement can be felt within 30 minutes to 1 hour after taking the tablet. Full treatment duration may vary depending on the condition being treated, but it is generally advised to take it for the shortest duration necessary. If there is no improvement after a few days, consult your doctor.

How to Use

Take the tablet with a full glass of water.

It can be taken with or without food.

Follow the dosage instructions given by your doctor or as per the package.

Do not crush or chew the tablet; swallow it whole.

Take it at the same time each day for best results.

Dosage Guidelines

Adult Dose

  • 1 tablet every 8-12 hours as needed, not exceeding 3 tablets in a day.

Pediatric Dose

Consult a doctor for appropriate dosing in children.

Elderly

Start with a lower dose and monitor for side effects.

Administration Instructions

Take with food to minimize stomach upset.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Overdose Warning

Overdose symptoms may include nausea, vomiting, and stomach pain. If you suspect an overdose, seek immediate medical attention or contact poison control.

Side Effects

Common Side Effects

Nausea

Stomach pain

Dizziness

Less Common Side Effects

Rash

Headache

Serious Side Effects

Severe allergic reactions

Stomach ulcers

When to Seek Immediate Medical Attention

If you experience severe abdominal pain, signs of an allergic reaction, or any unusual symptoms, seek medical help right away.

Contraindications — Who Should Not Use This Medicine

  • Allergy to NSAIDs — Risk of severe allergic reactions.
  • Active Peptic Ulcer — Can worsen the condition.
  • Severe Liver Disease — Risk of further liver damage.
  • Severe Kidney Disease — Risk of kidney failure.

Warnings & Precautions

🤰 Pregnancy
Pregnancy category is not well established. It is best to avoid use during pregnancy unless prescribed by a doctor.
🤱 Breastfeeding
Paracetamol is generally considered safe during breastfeeding, but consult your doctor before use.
👶 Children
Safety and effectiveness in children under 12 years have not been established. Consult a doctor for appropriate dosing.
🧓 Elderly
Elderly patients may be more sensitive to side effects. A lower dose may be recommended.
🫘 Kidney Disease
Use with caution in patients with kidney impairment. Dose adjustment may be necessary.
🫁 Liver Disease
Use with caution in patients with liver impairment. Regular monitoring may be required.
🍷 Alcohol
Avoid alcohol while taking this medication as it may increase the risk of liver damage.
🚗 Driving
This medicine may cause dizziness; use caution when driving or operating machinery.

Drug Interactions

Drug-Drug Interactions

Avoid taking with other NSAIDs

May interact with blood thinners

Food Interactions

Taking with food may help reduce stomach upset.

Alcohol Interactions

Alcohol can increase the risk of liver damage.

Disease Interactions

Use with caution in patients with a history of stomach ulcers or liver disease.

Storage Instructions

Store at room temperature (20-25°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check the expiry date before use.

Expert Advice

Clinical Tips

Take the medication as prescribed by your doctor.

Do not exceed the recommended dose.

Complete the full course of treatment.

Inform your doctor of any other medications you are taking.

Monitor for any unusual side effects.

Do not share your medication with others.

Keep track of your symptoms and report any changes to your doctor.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

Last Updated19 Jun 2026
Content Generated19 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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