ZYTHAM 200MG TABLET

by Zydus Healthcare Limited · Tablet Schedule H
Generic Name Ethambutol
Drug Class Antitubercular agent
Route Oral
Habit Forming No
Prescription Required (Rx)
Strengths 200mg, 400mg
MRP
₹9.42
strip of 10 tablets

About ZYTHAM 200MG TABLET

ZYTHAM 200MG TABLET contains Ethambutol, which is used to treat tuberculosis (TB). It works by stopping the growth of bacteria that cause TB. This medicine is usually part of a combination therapy, meaning it is used with other TB medications. It is important for patients with TB to complete the full course of treatment to effectively clear the infection. ZYTHAM 200MG TABLET is prescribed by a doctor and should be taken as directed. It is not suitable for everyone, so patients should discuss their medical history with their healthcare provider before starting this medication.

Clinical Uses

  • Tuberculosis — Used in combination with other medications to treat active tuberculosis infections.

Uses & Indications

Primary Uses

Treatment of active tuberculosis infections

Secondary Uses

Used as part of combination therapy for TBOff-label Uses

How It Works (Mechanism of Action)

ZYTHAM 200MG TABLET works by inhibiting the synthesis of the bacterial cell wall, which is essential for the bacteria's survival. This action helps stop the growth and multiplication of the bacteria causing tuberculosis.

Scientifically, Ethambutol interferes with the polymerization of arabinogalactan, an essential component of the mycobacterial cell wall. This disruption weakens the cell wall and leads to the death of the bacteria.

Key Benefits

  • Effective TB Treatment — Helps in the effective management of tuberculosis when used with other medications.
  • Prevents Bacterial Growth — Stops the growth of bacteria causing the infection.

How Long Does It Take to Work?

Initial improvement in symptoms may be noticed within a few weeks of starting treatment. However, the full course of treatment usually lasts several months, and it is important to complete the entire course as prescribed. If there is no improvement or symptoms worsen, consult your doctor.

How to Use

Take this medicine by mouth with a full glass of water.

It can be taken with or without food.

Follow the dosage schedule as prescribed by your doctor.

Do not skip doses, and complete the full course of treatment.

If you experience any side effects, inform your doctor.

Dosage Guidelines

Adult Dose

Typically, 15-25 mg/kg body weight per day, as prescribed by a doctor.

Pediatric Dose

Dosage is based on body weight and must be determined by a doctor.

Elderly

Dosage may need adjustment based on kidney function.

Administration Instructions

Take at the same time each day for best results.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Overdose Warning

In case of overdose, symptoms may include nausea, vomiting, dizziness, or confusion. Seek immediate medical attention or contact poison control. Do not wait for symptoms to appear.

Side Effects

Common Side Effects

Nausea

Loss of appetite

Stomach upset

Less Common Side Effects

Headache

Dizziness

Serious Side Effects

Vision changes

Severe skin rash

When to Seek Immediate Medical Attention

Signs of an allergic reaction, such as difficulty breathing or swelling of the face

Severe vision changes

Contraindications — Who Should Not Use This Medicine

  • Allergy to Ethambutol — Patients with known hypersensitivity should not use this medication.
  • Optic Neuritis — Patients with this condition should avoid using Ethambutol due to potential worsening of vision problems.

Warnings & Precautions

🤰 Pregnancy
Category C: There are no adequate and well-controlled studies in pregnant women. Ethambutol should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
🤱 Breastfeeding
Ethambutol is excreted in breast milk. Caution should be exercised when administered to a nursing woman. Discuss with your doctor if you are breastfeeding.
👶 Children
Ethambutol can be used in children, but the dosage must be carefully determined by a doctor based on the child's weight.
🧓 Elderly
Elderly patients may require dose adjustments due to potential kidney function impairment. Regular monitoring is advised.
🫘 Kidney Disease
Patients with renal impairment may require dose adjustments. Regular monitoring of kidney function is recommended.
🫁 Liver Disease
Use with caution in patients with liver impairment. Dose adjustment may be necessary based on liver function tests.
💉 Diabetes
Ethambutol does not directly affect blood sugar levels, but patients should monitor their condition as part of routine care.
🍷 Alcohol
Alcohol does not directly interact with Ethambutol, but it is advisable to limit alcohol consumption to avoid additional liver strain.
🚗 Driving
Ethambutol may cause dizziness or vision changes. Do not drive or operate heavy machinery if you experience these symptoms.

Drug Interactions

Drug-Drug Interactions

Antacids containing aluminum hydroxide may reduce the absorption of Ethambutol.

Food Interactions

No significant food interactions known.

Alcohol Interactions

Limit alcohol consumption to avoid liver strain.

Disease Interactions

Patients with optic neuritis should avoid Ethambutol.

Storage Instructions

Store at room temperature (20-25°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check the expiry date before use.

Expert Advice

Clinical Tips

Complete the full course of treatment even if you feel better.

Take the medicine at the same time each day.

Inform your doctor of any vision changes immediately.

Avoid missing doses to prevent resistance.

Discuss all medications you are taking with your doctor to avoid interactions.

Regular eye exams may be recommended during treatment.

Do not share your medication with others.

Inform your doctor if you are pregnant or breastfeeding.

Keep all follow-up appointments with your healthcare provider.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Frequently Asked Questions

How long will I need to take ZYTHAM?
The duration of treatment with ZYTHAM will depend on your specific condition and response to therapy, typically lasting several months.
What should I do if I miss a dose?
If you miss a dose of ZYTHAM, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule.
Can I stop taking ZYTHAM if I feel better?
No, it is important to complete the full course of ZYTHAM as prescribed, even if you start to feel better, to prevent the infection from returning.

Sources

The information on this page about ZYTHAM 200MG TABLET has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.

  1. Manufacturer – ZYTHAM 200MG TABLET Prescribing Information and Product Monograph
  2. NHSEthambutol
  3. Mayo ClinicEthambutol (Oral Route)
  4. MedlinePlusEthambutol
  5. Drugs.comEthambutol
Last Updated12 Jun 2026
Content Generated12 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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