Sipace Oral Suspension

Generic Name Paracetamol, Aceclofenac
Drug Class Analgesic, Antipyretic, Nonsteroidal Anti-inflammatory Drug (NSAID)
Route Oral
Habit Forming No
Prescription Required (Rx)
Strengths Paracetamol 125mg/5ml, Aceclofenac 50mg/5ml
MRP
₹46.00
bottle of 60 ml Oral Suspension

About Sipace Oral Suspension

Sipace Oral Suspension is a combination medicine containing Paracetamol and Aceclofenac. It is used to relieve pain and reduce fever in conditions such as headaches, toothaches, and joint pain. This medicine is suitable for both adults and children, but it should be used under medical supervision. It is important to follow the prescribed dosage to avoid any potential side effects. Patients with liver or kidney issues should consult their doctor before using this medication.

Clinical Uses

  • Pain Relief — Effective in reducing mild to moderate pain.
  • Fever Reduction — Helps in lowering high body temperature.
  • Inflammation — Reduces swelling and inflammation in conditions like arthritis.

Uses & Indications

Primary Uses

Pain relief in conditions like headaches, toothaches, and joint pain.

Reduction of fever.

Secondary Uses

Relief from pain and inflammation associated with arthritis.

Off-label Uses

How It Works (Mechanism of Action)

Sipace Oral Suspension works by combining the effects of Paracetamol and Aceclofenac. Paracetamol helps in reducing fever and relieving pain, while Aceclofenac reduces inflammation and pain.

Paracetamol works by inhibiting the synthesis of prostaglandins in the brain, which are chemicals responsible for pain and fever. Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that blocks the action of cyclooxygenase (COX) enzymes, reducing the formation of prostaglandins that cause inflammation and pain.

Key Benefits

  • Effective Pain Relief — Quickly alleviates mild to moderate pain.
  • Fever Reduction — Helps in bringing down high fever.
  • Anti-inflammatory — Reduces inflammation, providing comfort in conditions like arthritis.

How Long Does It Take to Work?

Initial improvement in pain and fever can be observed within 30 minutes to 1 hour after taking Sipace Oral Suspension. Full therapeutic effects may take a few days, especially for inflammation. If there is no improvement within 3 days, consult your doctor.

How to Use

Shake the bottle well before use.

Measure the prescribed dose using the measuring cup provided.

Take the suspension orally, with or without food.

Follow the dosage schedule as advised by your doctor.

Do not exceed the recommended dose.

Dosage Guidelines

Adult Dose

As prescribed by the physician, typically 5-10 ml every 8-12 hours.

Pediatric Dose

As prescribed by the physician, based on the child's weight and age.

Elderly

Use with caution, and follow the doctor's instructions.

Administration Instructions

Take with or without food.

Use the measuring cup provided for accurate dosing.

Missed Dose

If you miss a dose of Sipace Oral Suspension, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Overdose Warning

In case of an overdose, symptoms may include nausea, vomiting, stomach pain, dizziness, or drowsiness. Seek immediate medical attention or contact emergency services if an overdose is suspected.

Side Effects

Common Side Effects

Nausea

Stomach pain

Diarrhea

Less Common Side Effects

Dizziness

Rash

Serious Side Effects

Allergic reactions like swelling of the face, lips, or throat

Severe skin reactions

When to Seek Immediate Medical Attention

If you experience difficulty breathing, severe rash, or swelling.

Contraindications — Who Should Not Use This Medicine

  • Allergy — Patients with known allergy to Paracetamol, Aceclofenac, or any other NSAIDs should not use this medicine.
  • Severe Liver Disease — Not recommended for patients with severe liver impairment.
  • Severe Kidney Disease — Should be avoided in patients with severe renal impairment.

Warnings & Precautions

🤰 Pregnancy
Pregnancy Category C. Sipace Oral Suspension should be used during pregnancy only if clearly needed and prescribed by a doctor. Consult your healthcare provider for advice.
🤱 Breastfeeding
Sipace Oral Suspension should be used with caution during breastfeeding. Consult your doctor before use to ensure it is safe for you and your baby.
👶 Children
Sipace Oral Suspension can be used in children as prescribed by a doctor. Dosage is based on the child's weight and age.
🧓 Elderly
Elderly patients may use Sipace Oral Suspension with caution. Dosage adjustments may be necessary, and it should be used under medical supervision.
🫘 Kidney Disease
Patients with mild to moderate renal impairment should use Sipace Oral Suspension with caution. Dose adjustments may be necessary.
🫁 Liver Disease
Patients with liver impairment should use Sipace Oral Suspension with caution. Dose adjustments may be required based on liver function tests.
💉 Diabetes
Sipace Oral Suspension can be used by diabetic patients, but blood sugar levels should be monitored as a precaution.
🍷 Alcohol
Avoid consuming alcohol while taking Sipace Oral Suspension, as it may increase the risk of liver damage.
🚗 Driving
Sipace Oral Suspension does not usually affect your ability to drive. However, if you experience dizziness, avoid driving or operating machinery.

Drug Interactions

Drug-Drug Interactions

Other NSAIDs

Blood thinners like warfarin

Certain blood pressure medications

Food Interactions

Can be taken with or without food.

Alcohol Interactions

Avoid alcohol to prevent increased risk of liver damage.

Disease Interactions

Liver disease

Kidney disease

Storage Instructions

Store at room temperature (15-30°C).

Keep away from moisture.

Protect from light.

Keep out of reach of children.

Check the expiry date before use.

Expert Advice

Clinical Tips

Complete the full course as prescribed by your doctor.

Shake the bottle well before each use.

Use the measuring cup provided for accurate dosing.

Do not share your medication with others.

Inform your doctor about any other medications you are taking.

Avoid alcohol while using this medication.

Consult your doctor if symptoms persist or worsen.

Do not exceed the recommended dose.

Store the medicine properly as per instructions.

Substitute Medicines

Same composition, different brands. Always consult your doctor before switching.

Sources

The information on this page about Sipace Oral Suspension has been compiled and verified using the following authoritative medical sources and references. This content is AI-assisted and cross-checked against published clinical and pharmacological literature.

  1. Manufacturer – Sipace Oral Suspension Prescribing Information and Product Monograph
  2. NHSParacetamol: Uses, Side Effects, and More
  3. Drugs.comAceclofenac: Uses, Side Effects, and More
  4. MedlinePlusParacetamol (Acetaminophen)
  5. DrugBankAceclofenac
Last Updated13 Jun 2026
Content Generated13 Jun 2026
⚕️ Medical Disclaimer This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your doctor or pharmacist before starting, stopping, or changing any medication. Prices shown are indicative MRP and may vary.
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